2-<(4'-hydroxyphenyl)methyl>-3-methyl-4-hydroxy-5-propyl-7-chlorobenzofuran

Base Information

Chemical Name:2-<(4'-hydroxyphenyl)methyl>-3-methyl-4-hydroxy-5-propyl-7-chlorobenzofuran
CAS No.:102612-30-6
Molecular Formula:C₁₉H₁₉ClO₃
Molecular Weight:330.811
Hs Code.:

Synonyms:2-<(4'-hydroxyphenyl)methyl>-3-methyl-4-hydroxy-5-propyl-7-chlorobenzofuran

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-<(4'-hydroxyphenyl)methyl>-3-methyl-4-hydroxy-5-propyl-7-chlorobenzofuran

Chemical Property:

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Technology Process of 2-<(4'-hydroxyphenyl)methyl>-3-methyl-4-hydroxy-5-propyl-7-chlorobenzofuran

There total 4 articles about 2-<(4'-hydroxyphenyl)methyl>-3-methyl-4-hydroxy-5-propyl-7-chlorobenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 102612-16-8
4-hydroxy-7-chloro-2-<(4'-methoxyphenyl)methyl>-3-methyl-5-propylbenzofuran

: 102612-30-6
2-<(4'-hydroxyphenyl)methyl>-3-methyl-4-hydroxy-5-propyl-7-chlorobenzofuran

Guidance literature:: With boron tribromide;
DOI:10.1021/jm00126a008

Reference yield:

: 102624-59-9
2,6-dihydroxy-3-propyl-5-chloro-acetophenone

: 102612-30-6
2-<(4'-hydroxyphenyl)methyl>-3-methyl-4-hydroxy-5-propyl-7-chlorobenzofuran

Guidance literature:: Multi-step reaction with 3 steps

2: 75 percent / ZnI₂, NaCNBH₄ / 1,2-dichloro-ethane / 6 h / Heating

3: BBr₃

With boron tribromide; sodium cyanoborohydride; zinc(II) iodide; In 1,2-dichloro-ethane;
DOI:10.1021/jm00126a008

Reference yield:

: 120034-11-9
4-hydroxy-7-chloro-2-(p-methoxybenzoyl)-3-methyl-5-propylbenzofuran

: 102612-30-6
2-<(4'-hydroxyphenyl)methyl>-3-methyl-4-hydroxy-5-propyl-7-chlorobenzofuran

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / ZnI₂, NaCNBH₄ / 1,2-dichloro-ethane / 6 h / Heating

2: BBr₃

With boron tribromide; sodium cyanoborohydride; zinc(II) iodide; In 1,2-dichloro-ethane;
DOI:10.1021/jm00126a008