1-Amino-9-oxo-4-acridnecarboxylic acid

Base Information

• Chemical Name: 1-Amino-9-oxo-4-acridnecarboxylic acid
• CAS No.: 857616-10-5
• Molecular Formula: C₁₄H₁₀N₂O₃
• Molecular Weight: 254.245
• Mol file: 857616-10-5.mol

Synonyms:4-Acridancarboxylicacid, 1-amino-9-oxo- (4CI)

Chemical Property of 1-Amino-9-oxo-4-acridnecarboxylic acid

Chemical Property:

• PSA: 96.18000
• LogP: 2.54290

Purity/Quality:

99% ^*data from raw suppliers

1-AMINO-9-OXO-4-ACRIDNECARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Amino-9-oxo-4-acridnecarboxylic acid

There total 4 articles about 1-Amino-9-oxo-4-acridnecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-nitro-9-oxo-9,10-dihydroacridine-4-carboxylic acid (71507-04-5) → 1-amino-9-oxo-9,10-dihydro-acridine-4-carboxylic acid (857616-10-5)

Guidance literature:

With hydrogenchloride; acetic acid; tin(ll) chloride;

DOI:10.1021/ja01270a028

Reference yield:

2-chloro-4-nitrobenzoic acid (99-60-5) → 1-amino-9-oxo-9,10-dihydro-acridine-4-carboxylic acid (857616-10-5)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate; copper; amyl alcohol

2: PCl₅; nitrobenzene; AlCl₃

3: SnCl₂; concentrated aqueous HCl; acetic acid

With hydrogenchloride; aluminium trichloride; pentan-1-ol; phosphorus pentachloride; copper; potassium carbonate; acetic acid; nitrobenzene; tin(ll) chloride;

DOI:10.1021/ja01270a028

Reference yield:

2-((2-carboxyphenyl)amino)-4-nitrobenzoic acid (71835-14-8) → 1-amino-9-oxo-9,10-dihydro-acridine-4-carboxylic acid (857616-10-5)

Guidance literature:

Multi-step reaction with 2 steps

1: PCl₅; nitrobenzene; AlCl₃

2: SnCl₂; concentrated aqueous HCl; acetic acid

With hydrogenchloride; aluminium trichloride; phosphorus pentachloride; acetic acid; nitrobenzene; tin(ll) chloride;

DOI:10.1021/ja01270a028

upstream raw materials:

1-nitro-9-oxo-9,10-dihydroacridine-4-carboxylic acid

2-chloro-4-nitrobenzoic acid

2-((2-carboxyphenyl)amino)-4-nitrobenzoic acid

anthranilic acid

Downstream raw materials:

1-aminoacridin-9(10H)-one