2-(3-Methoxyphenyl)propanedial

Base Information

• Chemical Name: 2-(3-Methoxyphenyl)propanedial
• CAS No.: 857500-62-0
• Molecular Formula: C10H10 O3
• Molecular Weight: 178.188
• Hs Code.: 2923900090
• European Community (EC) Number: 674-345-6
• Mol file: 857500-62-0.mol

Synonyms:2-(3-methoxyphenyl)propanedial;2-(3-Methoxyphenyl)malondialdehyde;857500-62-0;2-(3-Methoxyphenyl)malonaldehyde;SCHEMBL2558825;MFCD02261923;AKOS006229039;CS-0252962;EN300-62118;A813329;Z979247236

Chemical Property of 2-(3-Methoxyphenyl)propanedial

Chemical Property:

• Melting Point: 61～64℃
• PSA: 43.37000
• LogP: 1.17660
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 178.062994177
• Heavy Atom Count: 13
• Complexity: 171

Purity/Quality:

98%min ^*data from raw suppliers

2-(3-Methoxyphenyl)malondialdehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)C(C=O)C=O

Technology Process of 2-(3-Methoxyphenyl)propanedial

There total 2 articles about 2-(3-Methoxyphenyl)propanedial which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H21N2O(1+)*ClO4(1-) → 3-MeOPhCH(CHO)2 (857500-62-0)

Guidance literature:

With sodium hydroxide; In water; at 90 ℃; for 0.25h;

DOI:10.1016/j.bmcl.2013.12.014

Reference yield:

m-methoxyphenylacetic acid (1798-09-0) → 3-MeOPhCH(CHO)2 (857500-62-0)

Guidance literature:

Multi-step reaction with 2 steps

1: trichlorophosphate; sodium perchlorate monohydrate / 5 - 95 °C

2: sodium hydroxide / water / 0.25 h / 90 °C

With sodium perchlorate monohydrate; sodium hydroxide; trichlorophosphate; In water;

DOI:10.1016/j.bmcl.2013.12.014

Reference yield:

3-MeOPhCH(CHO)2 (857500-62-0) + 4-hydrazinobenzene-1-sulfonamide hydrochloride (17852-52-7,27918-19-0) → 4-(4-(3-methoxyphenyl)-1H-pyrazol-1-yl)benzenesulfonamide

Guidance literature:

In ethanol; for 4h; Reflux;

DOI:10.1007/s11164-016-2620-x

upstream raw materials:

m-methoxyphenylacetic acid

Downstream raw materials:

4-(3-methoxyphenyl)-1-(4-nitrophenyl)-1H-pyrazole