ethyl (2R,4S)-2-(4-fluoro-2-methylphenyl)piperidine-4-carboxylate

Base Information

• Chemical Name: ethyl (2R,4S)-2-(4-fluoro-2-methylphenyl)piperidine-4-carboxylate
• CAS No.: 857357-08-5
• Molecular Formula: C₁₅H₂₀FNO₂
• Molecular Weight: 265.328
• DSSTox Substance ID: DTXSID301196776
• Mol file: 857357-08-5.mol

Synonyms:857357-08-5;SCHEMBL3162142;DTXSID301196776;ethyl (2R,4S)-2-(4-fluoro-2-methylphenyl)piperidine-4-carboxylate;Ethyl 2-(4-fluoro-2-methylphenyl)-4-piperidinecarboxylate

Chemical Property of ethyl (2R,4S)-2-(4-fluoro-2-methylphenyl)piperidine-4-carboxylate

Chemical Property:

• PSA: 38.33000
• LogP: 3.06670
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 265.14780704
• Heavy Atom Count: 19
• Complexity: 311

Purity/Quality:

99% ^*data from raw suppliers

ETHYL CIS-2-(4-FLUORO-2-METHYLPHENYL)PIPERIDINE-4-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(=O)C1CCNC(C1)C2=C(C=C(C=C2)F)C

Technology Process of ethyl (2R,4S)-2-(4-fluoro-2-methylphenyl)piperidine-4-carboxylate

There total 2 articles about ethyl (2R,4S)-2-(4-fluoro-2-methylphenyl)piperidine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-ethoxycarbonyl-2-(4-fluoro-2-methylphenyl)pyridine (629954-85-4) → 2,4-cis-4-ethoxycarbonyl-2-(4-fluoro-2-methylphenyl)piperidine (857357-08-5)

Guidance literature:

With hydrogenchloride; hydrogen; platinum(IV) oxide; In ethanol; water; at 20 ℃; for 5h;

Reference yield:

(2R,4S)-4-ethoxycarbonyl-2-(4-fluoro-2-methylphenyl)piperidine N-p-toluenesulfonyl-L-phenylalanine salt → (2R,4S)-4-ethoxycarbonyl-2-(4-fluoro-2-methylphenyl)piperidine (857357-08-5)

Guidance literature:

With ammonia; In water;

upstream raw materials:

4-ethoxycarbonyl-2-(4-fluoro-2-methylphenyl)pyridine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 857357-08-5 ETHYL CIS-2-(4-FLUORO-2-METHYLPHENYL)PIPERIDINE-4-CARBOXYLATE

Send

Send

Metric Ton KG G Pound L ML

Send

Send