(R,E)-benzyl 2-(((dimethylamino)methylene)carbamoyl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:(R,E)-benzyl 2-(((dimethylamino)methylene)carbamoyl)pyrrolidine-1-carboxylate
CAS No.:1140496-36-1
Molecular Formula:C₁₆H₂₁N₃O₃
Molecular Weight:303.361
Hs Code.:

Synonyms:(R,E)-benzyl 2-(((dimethylamino)methylene)carbamoyl)pyrrolidine-1-carboxylate

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Chemical Property of (R,E)-benzyl 2-(((dimethylamino)methylene)carbamoyl)pyrrolidine-1-carboxylate

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Technology Process of (R,E)-benzyl 2-(((dimethylamino)methylene)carbamoyl)pyrrolidine-1-carboxylate

There total 1 articles about (R,E)-benzyl 2-(((dimethylamino)methylene)carbamoyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 62937-47-7,58274-22-9
(2R)-2-carbamoyl-pyrrolidine-1-carboxylic acid benzyl ester

: 1140496-36-1
(R,E)-benzyl 2-(((dimethylamino)methylene)carbamoyl)pyrrolidine-1-carboxylate

Guidance literature:: In N,N-dimethyl-formamide dimethyl acetal; at 120 ℃; for 2h;

Reference yield:

: 1140496-39-4
4-chlorobenzyl-hydrazine acetate

: 1140496-36-1
(R,E)-benzyl 2-(((dimethylamino)methylene)carbamoyl)pyrrolidine-1-carboxylate

: 1140496-38-3
(R)-benzyl 2-(2-(4-chlorobenzyl)-2H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate

Guidance literature:: 4-chlorobenzyl-hydrazine acetate; (R,E)-benzyl 2-(((dimethylamino)methylene)carbamoyl)pyrrolidine-1-carboxylate; With acetic acid; at 90 ℃; for 1.5h;

With sodium hydrogencarbonate; In water; ethyl acetate;