N-[(5-hydroxy-6-(1-methylethyl)-3-oxo-2-{[4-(4-pyridinyl)phenyl]methyl}-2,3-dihydro-4-pyridazinyl)carbonyl]glycine

Base Information

Chemical Name:N-[(5-hydroxy-6-(1-methylethyl)-3-oxo-2-{[4-(4-pyridinyl)phenyl]methyl}-2,3-dihydro-4-pyridazinyl)carbonyl]glycine
CAS No.:1040538-96-2
Molecular Formula:C₂₂H₂₂N₄O₅
Molecular Weight:422.44
Hs Code.:

Synonyms:N-[(5-hydroxy-6-(1-methylethyl)-3-oxo-2-{[4-(4-pyridinyl)phenyl]methyl}-2,3-dihydro-4-pyridazinyl)carbonyl]glycine

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Chemical Property of N-[(5-hydroxy-6-(1-methylethyl)-3-oxo-2-{[4-(4-pyridinyl)phenyl]methyl}-2,3-dihydro-4-pyridazinyl)carbonyl]glycine

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Technology Process of N-[(5-hydroxy-6-(1-methylethyl)-3-oxo-2-{[4-(4-pyridinyl)phenyl]methyl}-2,3-dihydro-4-pyridazinyl)carbonyl]glycine

There total 1 articles about N-[(5-hydroxy-6-(1-methylethyl)-3-oxo-2-{[4-(4-pyridinyl)phenyl]methyl}-2,3-dihydro-4-pyridazinyl)carbonyl]glycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 1040538-72-4
N-{[2-[(4-bromophenyl)methyl]-5-hydroxy-6-(1-methylethyl)-3-oxo-2,3-dihydro-4-pyridazinyl]carbonyl}glycine

: 1692-15-5
4-pyridylboronic acid

: 1040538-96-2
N-[(5-hydroxy-6-(1-methylethyl)-3-oxo-2-{[4-(4-pyridinyl)phenyl]methyl}-2,3-dihydro-4-pyridazinyl)carbonyl]glycine

Guidance literature:: N-{[2-[(4-bromophenyl)methyl]-5-hydroxy-6-(1-methylethyl)-3-oxo-2,3-dihydro-4-pyridazinyl]carbonyl}glycine; 4-pyridylboronic acid; With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; at 100 ℃; for 0.333333h; Microwave heating;

With hydrogenchloride; In 1,4-dioxane; water; Acidic conditions;