Technology Process of 2,5-di(5'-hydroxypentyl)-1,4-diiodobenzene
There total 6 articles about 2,5-di(5'-hydroxypentyl)-1,4-diiodobenzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: Mg / diethyl ether / Heating
1.2: 38 percent / dichloro[1,3-bis(diphenylphosphino)propane]nickel / diethyl ether / Heating
2.1: BH3*THF / tetrahydrofuran / 3 h / 50 °C
2.2: 97 percent / NaOH; H2O2 / H2O; tetrahydrofuran / 20 °C
3.1: 100 percent / pyridine / 20 °C
4.1: 92 percent / I2; H5IO6 / acetic acid; aq. H2SO4 / 3 h / 80 °C
5.1: 95 percent / K2CO3 / methanol; CH2Cl2 / 20 °C
With
pyridine; borane-THF; iodine; potassium carbonate; magnesium; periodic acid;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; sulfuric acid; acetic acid;
1.1: Metallation / 1.2: cross-coupling / 2.1: hydroboration / 2.2: Oxidation / 3.1: Acetylation / 4.1: Iodination / 5.1: Hydrolysis;
DOI:10.1021/jo991201s
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 92 percent / I2; H5IO6 / acetic acid; aq. H2SO4 / 3 h / 80 °C
2: 95 percent / K2CO3 / methanol; CH2Cl2 / 20 °C
With
iodine; potassium carbonate; periodic acid;
In
methanol; dichloromethane; sulfuric acid; acetic acid;
1: Iodination / 2: Hydrolysis;
DOI:10.1021/jo991201s
![acetic acid 5-[4-(5-acetoxy-pentyl)-2,5-diiodo-phenyl]-pentyl ester](/Databaselist/images/loading.webp)
