O-(2-O-Acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl) trichloroacetimidate

Base Information

• Chemical Name: O-(2-O-Acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl) trichloroacetimidate
• CAS No.: 130177-78-5
• Molecular Formula: C₃₁H₃₂Cl₃NO₇
• Molecular Weight: 636.957
• Mol file: 130177-78-5.mol

Synonyms:O-(2-O-Acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl) trichloroacetimidate

Chemical Property of O-(2-O-Acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl) trichloroacetimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-(2-O-Acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl) trichloroacetimidate

There total 22 articles about O-(2-O-Acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl) trichloroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-O-acetyl-3,4,6-tri-O-benzyl-D-mannopyranoside (129214-38-6) + trichloroacetonitrile (545-06-2) → 2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl trichloroacetimidate (108869-64-3,130177-78-5,129163-12-8)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1,2-dichloro-ethane; for 0.166667h;

DOI:10.1016/0008-6215(90)84223-H

Reference yield: 93.0%

ethyl 2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranoside (79218-68-1) + trichloroacetonitrile (545-06-2) → 2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl trichloroacetimidate (108869-64-3,130177-78-5,129163-12-8)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene;

Reference yield: 83.0%

2-O-acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranose (79218-68-1,88988-46-9,93495-88-6,108869-76-7,127875-27-8,127875-34-7,129214-38-6,148968-88-1) + trichloroacetonitrile (545-06-2) → O-(2-O-Acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl) trichloroacetimidate (130177-78-5)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane;

DOI:10.1002/hlca.19940770211

upstream raw materials:

1,2-di-O-acetyl-3,4,6-tri-O-benzyl-D-galactopyranose

trichloroacetonitrile

2-O-acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranose

allyl 2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranoside

Downstream raw materials:

allyl 2-O-(2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-3,4-di-O-benzyl-β-D-xylopyranoside

tert-Butyldimethylsilyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1-4)-3-O-benzyl-β-D-xylopyranoside

allyl 2-acetamido-3-O-(2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-2-deoxy-4,6-di-O-pivaloyl-β-D-galactopyranoside

allyl 2-O-acetyl-3,4,6-tri-O-benzyl-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-4,6-di-O-pivaloyl-β-D-galactopyranosyl-(1->3)-2,4,6-tri-O-benzyl-α-D-galactopyranoside