[(3S)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]acetic acid (1R)-1-phenylethylamine salt

Base Information

Chemical Name:[(3S)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]acetic acid (1R)-1-phenylethylamine salt
CAS No.:1394138-46-5
Molecular Formula:C₈H₁₁N*C₁₀H₁₀O₄
Molecular Weight:315.369
Hs Code.:

Synonyms:[(3S)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]acetic acid (1R)-1-phenylethylamine salt

Suppliers and Price of [(3S)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]acetic acid (1R)-1-phenylethylamine salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-1-phenylethanamine(S)-2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate
50mg
$ 90.00

ChemScene
(R)-1-phenylethanamine(S)-2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate
5g
$ 1200.00

ChemScene
(R)-1-phenylethanamine(S)-2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate
1g
$ 350.00

Total 3 raw suppliers

Chemical Property of [(3S)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]acetic acid (1R)-1-phenylethylamine salt

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

(R)-1-phenylethanamine(S)-2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of [(3S)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]acetic acid (1R)-1-phenylethylamine salt

There total 7 articles about [(3S)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]acetic acid (1R)-1-phenylethylamine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 69716-04-7
2-(6-hydroxy-1-benzofuran-3-yl)acetic acid

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 1394138-46-5
[(3S)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]acetic acid (1R)-1-phenylethylamine salt

Guidance literature:: With hydrogen; dichloro [(+)-1,2-bis((2R,5R)-2,5-diisopropylphosphorano)benzene]ruthenium (II)-N,N-dimethylformamide complex; In methanol; at 35 ℃; for 18h; under 6375.64 Torr;

Reference yield:

: 1000414-37-8
2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetic acid

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 1394138-46-5
[(3S)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]acetic acid (1R)-1-phenylethylamine salt

Guidance literature:: In acetonitrile; for 10h; Reflux;
DOI:10.1016/j.bmc.2017.12.030

Reference yield:

: 25392-41-0
4-chloromethyl-7-hydroxycoumarin

: 1394138-46-5
[(3S)-6-hydroxy-2,3-dihydro-1-benzofuran-3-yl]acetic acid (1R)-1-phenylethylamine salt

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide; water / water / 5 h / 5 - 60 °C

1.2: 35 °C

2.1: hydrogen / dichloro [(+)-1,2-bis((2R,5R)-2,5-diisopropylphosphorano)benzene]ruthenium (II)-N,N-dimethylformamide complex / methanol / 18 h / 35 °C / 6375.64 Torr

With water; hydrogen; sodium hydroxide; dichloro [(+)-1,2-bis((2R,5R)-2,5-diisopropylphosphorano)benzene]ruthenium (II)-N,N-dimethylformamide complex; In methanol; water;