3-Bromo-2,6-difluorobenzonitrile

Base Information

• Chemical Name: 3-Bromo-2,6-difluorobenzonitrile
• CAS No.: 1250444-23-5
• Molecular Formula: C₇H₂BrF₂N
• Molecular Weight: 218
• Hs Code.: 2926907090
• Mol file: 1250444-23-5.mol

Synonyms:4-bromo-2,6-difluorobenzenonitrile

Chemical Property of 3-Bromo-2,6-difluorobenzonitrile

Chemical Property:

• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

3-Bromo-2,6-difluorobenzonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Bromo-2,6-difluorobenzonitrile

There total 3 articles about 3-Bromo-2,6-difluorobenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2,6 difluorobenzonitrile (1897-52-5) → 4-bromo-2,6-difluorobenzenonitrile (1250444-23-5)

Guidance literature:

With potassium bromate; sulfuric acid; at 35 ℃; Inert atmosphere;

Reference yield: 70.0%

2,6 difluorobenzonitrile (1897-52-5) → 3-bromo-2,6-difluorobenzamide (1541810-83-6) + 4-bromo-2,6-difluorobenzenonitrile (1250444-23-5)

Guidance literature:

With N-Bromosuccinimide; sulfuric acid; at 0 - 20 ℃; for 24h;

Reference yield:

3-amino-2,6-difluoro-benzonitrile (143879-78-1) → 4-bromo-2,6-difluorobenzenonitrile (1250444-23-5)

Guidance literature:

With tert.-butylnitrite; copper(ll) bromide; In acetonitrile; at 65 ℃; for 1h;

upstream raw materials:

2,6 difluorobenzonitrile

3-amino-2,6-difluoro-benzonitrile