17alpha-Hydroxy-1alpha,2alpha-methylene-4,6-pregnadiene-3,20-dione

Base Information

Chemical Name:17alpha-Hydroxy-1alpha,2alpha-methylene-4,6-pregnadiene-3,20-dione
CAS No.:2098-65-9
Molecular Formula:C₂₂H₂₈O₃
Molecular Weight:340.463
Hs Code.:
European Community (EC) Number:606-682-1
DSSTox Substance ID:DTXSID401128728

Synonyms:SCHEMBL5596318;HEQOAVAMLQHQHC-BCJMKXOLSA-N;DTXSID401128728;17alpha-hydroxy-1alpha,2alpha-methylene-4,6-pregnadiene-3,20-dione;2098-65-9;3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 1,2-dihydro-17-hydroxy-, (1alpha,2alpha)-

Suppliers and Price of 17alpha-Hydroxy-1alpha,2alpha-methylene-4,6-pregnadiene-3,20-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3''H-Cyclopropa[1,2]cyclopenta[a]phenanthrene
5mg
$ 220.00

Total 1 raw suppliers

Chemical Property of 17alpha-Hydroxy-1alpha,2alpha-methylene-4,6-pregnadiene-3,20-dione

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:340.20384475
Heavy Atom Count:25
Complexity:748

Purity/Quality:

99.9% ^*data from raw suppliers

3''H-Cyclopropa[1,2]cyclopenta[a]phenanthrene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1(CCC2C1(CCC3C2C=CC4=CC(=O)C5CC5C34C)C)O
Isomeric SMILES:CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=CC4=CC(=O)[C@@H]5C[C@@H]5[C@]34C)C)O
Uses 3''H-Cyclopropa[1,2]cyclopenta[a]phenanthrene is a water soluble gestational steroid.

Technology Process of 17alpha-Hydroxy-1alpha,2alpha-methylene-4,6-pregnadiene-3,20-dione

There total 9 articles about 17alpha-Hydroxy-1alpha,2alpha-methylene-4,6-pregnadiene-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₃H₃₀O₄

: 25596-24-1
trimethyloxosulfonium bromide

: 2098-65-9
17α-hydroxy-1α,2α-methylene-4,6-pregnadiene-3,20-dione

Guidance literature:: C₂₃H₃₀O₄; trimethyloxosulfonium bromide; With sodium hydroxide; In N,N-dimethyl-formamide; at 42 - 45 ℃; for 3h;

With sulfuric acid; In N,N-dimethyl-formamide; for 2h; pH=2;

Reference yield:

: C₂₄H₃₂O₄

: 2098-65-9
17α-hydroxy-1α,2α-methylene-4,6-pregnadiene-3,20-dione

Guidance literature:: With sulfuric acid; In N,N-dimethyl-formamide; for 2h; pH=2;

Reference yield:

: 66212-25-7
1,4,6-triene-3,20-dione-17α-hydroxyprogesterone

: 2098-65-9
17α-hydroxy-1α,2α-methylene-4,6-pregnadiene-3,20-dione

Guidance literature:: Multi-step reaction with 3 steps

1: orthoformic acid triethyl ester / dichloromethane / 5 h / 30 °C

2: N,N-dimethyl-formamide / 3 h / 42 °C

3: sulfuric acid / N,N-dimethyl-formamide / 2 h / pH 2

With sulfuric acid; orthoformic acid triethyl ester; In dichloromethane; N,N-dimethyl-formamide;