(E)-2-(benzoylamino)-3-[2-(4-chlorophenyl)-4-hydroxy-6-methylpyrimidin-5-yl]propenoic acid

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Chemical Name:(E)-2-(benzoylamino)-3-[2-(4-chlorophenyl)-4-hydroxy-6-methylpyrimidin-5-yl]propenoic acid
CAS No.:1192144-47-0
Molecular Formula:C₂₁H₁₆ClN₃O₄
Molecular Weight:409.829
Hs Code.:

Synonyms:(E)-2-(benzoylamino)-3-[2-(4-chlorophenyl)-4-hydroxy-6-methylpyrimidin-5-yl]propenoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-2-(benzoylamino)-3-[2-(4-chlorophenyl)-4-hydroxy-6-methylpyrimidin-5-yl]propenoic acid

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Technology Process of (E)-2-(benzoylamino)-3-[2-(4-chlorophenyl)-4-hydroxy-6-methylpyrimidin-5-yl]propenoic acid

There total 1 articles about (E)-2-(benzoylamino)-3-[2-(4-chlorophenyl)-4-hydroxy-6-methylpyrimidin-5-yl]propenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 97497-15-9
ethyl 3-(benzoylamino)-6-methyl-2-oxo-2H-pyran-5-carboxylate

: 115297-57-9
4-chlorobenzene-1-carboximidamide hydrogeniodide

: 1192144-47-0
(E)-2-(benzoylamino)-3-[2-(4-chlorophenyl)-4-hydroxy-6-methylpyrimidin-5-yl]propenoic acid

Guidance literature:: ethyl 3-(benzoylamino)-6-methyl-2-oxo-2H-pyran-5-carboxylate; 4-chlorobenzene-1-carboximidamide hydrogeniodide; With sodium carbonate; In ethanol; water; at 100 ℃; for 0.5h; Microwave irradiation;

With hydrogenchloride; In water; pH=2;
DOI:10.1016/j.tet.2009.07.072