N¹⁵,N²⁹-desmethyl RA-VII

Base Information

Chemical Name:N¹⁵,N²⁹-desmethyl RA-VII
CAS No.:138571-36-5
Molecular Formula:C₃₉H₄₆N₆O₉
Molecular Weight:742.829
Hs Code.:

N<sup>15</sup>,N<sup>29</sup>-desmethyl RA-VII

Synonyms:N¹⁵,N²⁹-desmethyl RA-VII

Suppliers and Price of N¹⁵,N²⁹-desmethyl RA-VII

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N¹⁵,N²⁹-desmethyl RA-VII

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N¹⁵,N²⁹-desmethyl RA-VII

There total 14 articles about N¹⁵,N²⁹-desmethyl RA-VII which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 138571-41-2
(9S,12S)-12-{(S)-2-[(S)-2-{[(S)-2-((R)-2-Amino-propionylamino)-propionyl]-methyl-amino}-3-(4-methoxy-phenyl)-propionylamino]-propionylamino}-4-methoxy-11-oxo-2-oxa-10-aza-tricyclo[12.2.2.1^3,7]nonadeca-1⁽¹⁷⁾,3⁽¹⁹⁾,4,6,14⁽¹⁸⁾,15-hexaene-9-carboxylic acid; hydrochloride

: 138571-36-5
N¹⁵,N²⁹-desmethyl RA-VII

Guidance literature:: With diphenylphosphoranyl azide; sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 4 ℃; for 48h;
DOI:10.1021/ja00133a010

Reference yield:

: 112196-84-6
BOC-D-Ala-L-Ala-NMe-L-Tyr(OMe)-L-Ala-OH

: 138571-36-5
N¹⁵,N²⁹-desmethyl RA-VII

Guidance literature:: Multi-step reaction with 5 steps

1: 75 percent / EDCI / CH₂Cl₂ / 4 h / 25 °C

2: 87 percent / tetrahydrofuran / 2 h / 25 °C

3: 93 percent / aq. LiOH / tetrahydrofuran; methanol / 8 h / 25 °C

4: 100 percent / HCl / ethyl acetate / 1.) 0 deg C, 10 min, 2.) 25 deg C, 50 min

5: 80 percent / NaHCO₃, diphenylphosphoryl Azide / dimethylformamide / 48 h / 4 °C

With hydrogenchloride; lithium hydroxide; diphenylphosphoranyl azide; sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/ja00133a010

Reference yield:

: 138571-40-1
C₄₄H₅₆N₆O₁₂

: 138571-36-5
N¹⁵,N²⁹-desmethyl RA-VII

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / HCl / ethyl acetate / 1.) 0 deg C, 10 min, 2.) 25 deg C, 50 min

2: 80 percent / NaHCO₃, diphenylphosphoryl Azide / dimethylformamide / 48 h / 4 °C

With hydrogenchloride; diphenylphosphoranyl azide; sodium hydrogencarbonate; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/ja00133a010