C₂₈H₂₄ClNO₃

Base Information

• Chemical Name: C₂₈H₂₄ClNO₃
• CAS No.: 1075277-71-2
• Molecular Formula: C₂₈H₂₄ClNO₃
• Molecular Weight: 457.956
• Mol file: 1075277-71-2.mol

Synonyms:C₂₈H₂₄ClNO₃

Chemical Property of C₂₈H₂₄ClNO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₂₄ClNO₃

There total 3 articles about C₂₈H₂₄ClNO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

methyl 2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate (149968-11-6) → C28H24ClNO3 (1075277-71-2) + C28H26ClNO3 + methyl-[(E)]-2-[3(S)-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl] benzoate (181139-72-0)

Guidance literature:

With formic acid; caesium carbonate; In N,N-dimethyl-formamide; at 40 ℃; for 24h; Product distribution / selectivity;

Reference yield:

methyl 2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate (149968-11-6) → C28H24ClNO3 (1075277-71-2)

Guidance literature:

With lithium methanolate; hydrogen; (R)-N,N-dimethyl-1-[(S)-1',2-bis (diphenylphosphino) ferrocenyl] ethylamine; diiodo(p-cymene)ruthenium(II) dimer; In tetrahydrofuran; methanol; isopropyl alcohol; at 20 ℃; for 16h; under 3750.38 Torr; Product distribution / selectivity; Combinatorial reaction / High throughput screening (HTS);

Reference yield:

methyl 2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate (149968-11-6) → methyl 2-(3-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3(R)-3-hydroxypropyl)benzoate + C28H24ClNO3 (1075277-71-2)

Guidance literature:

With lithium methanolate; hydrogen; diiodo(p-cymene)ruthenium(II) dimer; (R)-(+)-2,2',6,6'-tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine; In tetrahydrofuran; methanol; isopropyl alcohol; at 20 ℃; for 16h; under 3750.38 Torr; Product distribution / selectivity; Combinatorial reaction / High throughput screening (HTS);

upstream raw materials:

methyl 2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate

Refernces

• 1、 -. "PROCESS". Page/Page column 11. . Retrieved 2008/06/13.