Technology Process of (2R,3R,4S)-2,3,4,6-tetrakis(benzyloxy)-5-oxohexanal
There total 7 articles about (2R,3R,4S)-2,3,4,6-tetrakis(benzyloxy)-5-oxohexanal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
oxalyl dichloride; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran;
at -65 - 20 ℃;
for 1.75h;
DOI:10.1021/jo980831b
-
-
4291-69-4,6386-24-9,6564-72-3,59531-24-7,69257-52-9,78184-89-1,78609-16-2,78609-17-3,78609-18-4,96553-53-6,104111-61-7,131347-08-5,4132-28-9
2,3,4,6-Tetra-O-benzyl-D-glucopyranose
- Guidance literature:
-
Multi-step reaction with 2 steps
1: LiAlH4 / tetrahydrofuran / 20 h / 0 - 20 °C
2: oxalylchloride; DMSO; Et3N / CH2Cl2 / 4.42 h / -75 - -5 °C
With
lithium aluminium tetrahydride; Chloro-oxo-acetic acid; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; dichloromethane;
2: Swern oxidation;
DOI:10.1021/jo061280p
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 100 percent / LiAlH4 / tetrahydrofuran / Ambient temperature
2: 1.) TFAA, DMSO, 2.) Et3N / 1.) CH2Cl2, -78 deg C, 1.5 h, 2.) CH2Cl2, -78 deg C to r.t., 30 min
With
lithium aluminium tetrahydride; dimethyl sulfoxide; triethylamine; trifluoroacetic anhydride;
In
tetrahydrofuran;
DOI:10.1055/s-1999-3430
