5-(morpholinomethyl)-6-phenyl-N-(2-(thiazolo[5,4-b]pyridin-2-yl)phenyl)picolinamide

Base Information

• Chemical Name: 5-(morpholinomethyl)-6-phenyl-N-(2-(thiazolo[5,4-b]pyridin-2-yl)phenyl)picolinamide
• CAS No.: 1152094-54-6
• Molecular Formula: C₂₉H₂₅N₅O₂S
• Molecular Weight: 507.616
• Mol file: 1152094-54-6.mol

Synonyms:5-(morpholinomethyl)-6-phenyl-N-(2-(thiazolo[5,4-b]pyridin-2-yl)phenyl)picolinamide

Chemical Property of 5-(morpholinomethyl)-6-phenyl-N-(2-(thiazolo[5,4-b]pyridin-2-yl)phenyl)picolinamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 5-(morpholinomethyl)-6-phenyl-N-(2-(thiazolo[5,4-b]pyridin-2-yl)phenyl)picolinamide

There total 1 articles about 5-(morpholinomethyl)-6-phenyl-N-(2-(thiazolo[5,4-b]pyridin-2-yl)phenyl)picolinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(thiazolo[5,4-b]pyridin-2-yl)aniline (1152096-24-6) + 5-(morpholinomethyl)-6-phenylpicolinic acid (1152095-55-0) → 5-(morpholinomethyl)-6-phenyl-N-(2-(thiazolo[5,4-b]pyridin-2-yl)phenyl)picolinamide (1152094-54-6)

Guidance literature:

5-(morpholinomethyl)-6-phenylpicolinic acid; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;

2-(thiazolo[5,4-b]pyridin-2-yl)aniline; In N,N-dimethyl-formamide; at 40 ℃; for 60h;

Reference yield:

5-(morpholinomethyl)-6-phenyl-N-(2-(thiazolo[5,4-b]pyridin-2-yl)phenyl)picolinamide (1152094-54-6) → 5-(morpholinomethyl)-6-phenyl-N-(2-(thiazolo[5,4-b]pyridin-2-yl)phenyl)picolinamide hydrochloride (1152095-56-1)

Guidance literature:

With hydrogenchloride; In methanol;

upstream raw materials:

2-(thiazolo[5,4-b]pyridin-2-yl)aniline

5-(morpholinomethyl)-6-phenylpicolinic acid

Downstream raw materials:

5-(morpholinomethyl)-6-phenyl-N-(2-(thiazolo[5,4-b]pyridin-2-yl)phenyl)picolinamide hydrochloride