(3R)-1-[(S)-1-phenylethyl]mevalonamide

Base Information

• Chemical Name: (3R)-1-[(S)-1-phenylethyl]mevalonamide
• CAS No.: 946831-51-2
• Molecular Formula: C₁₄H₂₁NO₃
• Molecular Weight: 251.326
• Mol file: 946831-51-2.mol

Synonyms:(3R)-1-[(S)-1-phenylethyl]mevalonamide

Chemical Property of (3R)-1-[(S)-1-phenylethyl]mevalonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (3R)-1-[(S)-1-phenylethyl]mevalonamide

There total 52 articles about (3R)-1-[(S)-1-phenylethyl]mevalonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

C53H76O6N2 (946831-50-1) → (3R)-1-[(S)-1-phenylethyl]mevalonamide (946831-51-2)

Guidance literature:

With lithium borohydride; In tetrahydrofuran; at 0 - 20 ℃; for 12h;

DOI:10.1016/j.tetasy.2007.05.013

Reference yield:

C41H49NO17 → (3R)-1-[(S)-1-phenylethyl]mevalonamide (946831-51-2)

Guidance literature:

With lithium borohydride; In tetrahydrofuran; at 0 - 20 ℃; for 3h;

DOI:10.1016/j.bioorg.2018.06.024

Reference yield:

C38H45NO14 → (3R)-1-[(S)-1-phenylethyl]mevalonamide (946831-51-2)

Guidance literature:

With lithium borohydride; In tetrahydrofuran; at 25 ℃; for 24h; Cooling with ice;

DOI:10.1016/j.fitote.2019.04.002

upstream raw materials:

(3S)-1-<(S)-Phenylethyl>-5-methoxy-3-hydroxy-3-methylglutaroamide

(S)-1-phenyl-ethylamine

(R)-mevalonolactone

C₅₃H₇₆O₆N₂

Downstream raw materials:

(3R)-5-O-acetyl-1-<(S)-phenylethyl>-mevalonamide