1-(2-phenylsulfinylethyl)-2-benzoylpyrrole

Base Information

• Chemical Name: 1-(2-phenylsulfinylethyl)-2-benzoylpyrrole
• CAS No.: 87549-08-4
• Molecular Formula: C₁₉H₁₇NO₂S
• Molecular Weight: 323.415
• Mol file: 87549-08-4.mol

Synonyms:1-(2-phenylsulfinylethyl)-2-benzoylpyrrole

Chemical Property of 1-(2-phenylsulfinylethyl)-2-benzoylpyrrole

Chemical Property:

Purity/Quality:

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Technology Process of 1-(2-phenylsulfinylethyl)-2-benzoylpyrrole

There total 4 articles about 1-(2-phenylsulfinylethyl)-2-benzoylpyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-(2-phenylsulfenylethyl)-2-benzoylpyrrole (87549-09-5) → 1-(2-phenylsulfinylethyl)-2-benzoylpyrrole (87549-08-4)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 1h;

Reference yield: 86.0%

phenyl(1H-pyrrol-2-yl)methanone (7697-46-3) + chloroethyl phenyl sulfoxide (27998-60-3) → 1-(2-phenylsulfinylethyl)-2-benzoylpyrrole (87549-08-4)

Guidance literature:

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; In benzene; for 24h; Heating;

Reference yield:

phenyl(1H-pyrrol-2-yl)methanone (7697-46-3) → 1-(2-phenylsulfinylethyl)-2-benzoylpyrrole (87549-08-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 89 percent / 50percent aq. sodium hydroxide/tetra-n-butylammonium iodide / 1 h / Heating

2: 88 percent / 50percent sodium hydride in oil / dimethylformamide / 2 h

3: 88 percent / 85percent m-chloroperbenzoic acid / CH₂Cl₂ / 1 h / 0 °C

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; sodium hydride; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; N,N-dimethyl-formamide;

upstream raw materials:

phenyl(1H-pyrrol-2-yl)methanone

chloroethyl phenyl sulfoxide

1-(2-phenylsulfenylethyl)-2-benzoylpyrrole

1-(2-chloroethyl)-2-benzoylpyrrole

Downstream raw materials:

phenyl(1H-pyrrol-2-yl)methanone

Refernces