C₃₀H₄₀N₆O₁₁

Base Information

• Chemical Name: C₃₀H₄₀N₆O₁₁
• CAS No.: 1608113-30-9
• Molecular Formula: C₃₀H₄₀N₆O₁₁
• Molecular Weight: 660.681
• Mol file: 1608113-30-9.mol

Synonyms:C₃₀H₄₀N₆O₁₁

Chemical Property of C₃₀H₄₀N₆O₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₄₀N₆O₁₁

There total 8 articles about C₃₀H₄₀N₆O₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

C50H56N6O12 (1608113-29-6) → C30H40N6O11 (1608113-30-9)

Guidance literature:

With acetic acid; In dichloromethane; at 20 ℃; for 3.5h; Inert atmosphere;

DOI:10.1002/ejoc.201301781

Reference yield:

C18H28N4O8 → C30H40N6O11 (1608113-30-9)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium hydrogencarbonate / tetrahydrofuran; water / 16 h / 0 - 20 °C / Inert atmosphere

2: methyl-phenyl-thioether / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere

3: triethylamine / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere

4: acetic acid / dichloromethane / 3.5 h / 20 °C / Inert atmosphere

With methyl-phenyl-thioether; sodium hydrogencarbonate; acetic acid; triethylamine; In tetrahydrofuran; dichloromethane; water;

DOI:10.1002/ejoc.201301781

Reference yield:

thymidine (50-89-5,28854-96-8,3545-96-8,50-88-4) → C30H40N6O11 (1608113-30-9)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine; dmap / N,N-dimethyl-formamide / 4 h / 20 °C / Inert atmosphere

2: pyridine / dichloromethane / 24 h / 0 - 20 °C / Inert atmosphere

3: triethylamine / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere

4: acetic acid / dichloromethane / 3.5 h / 20 °C / Inert atmosphere

With pyridine; dmap; acetic acid; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/ejoc.201301781

upstream raw materials:

thymidine

N-For-Gly-L-Lys(Boc)-L-Phe-OMe

N-For-Gly-L-Lys(NH₂*TFA)-L-Phe-OMe

5'-O-(4-monomethoxytrityl)-2'-deoxythymidine

Downstream raw materials:

C₄₄H₅₃N₆O₁₄P