2,7-bis(trimethylsilyl)-9-fluorenylmethyl carbanilate

Base Information

• Chemical Name: 2,7-bis(trimethylsilyl)-9-fluorenylmethyl carbanilate
• CAS No.: 136453-40-2
• Molecular Formula: C₂₇H₃₃NO₂Si₂
• Molecular Weight: 459.736
• Mol file: 136453-40-2.mol

Synonyms:2,7-bis(trimethylsilyl)-9-fluorenylmethyl carbanilate

Chemical Property of 2,7-bis(trimethylsilyl)-9-fluorenylmethyl carbanilate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,7-bis(trimethylsilyl)-9-fluorenylmethyl carbanilate

There total 5 articles about 2,7-bis(trimethylsilyl)-9-fluorenylmethyl carbanilate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.13%

phenyl isocyanate (103-71-9) + 2,7-bis(trimethylsilyl)fluorene-9-methanol (136453-41-3) → 2,7-bis(trimethylsilyl)-9-fluorenylmethyl carbanilate (136453-40-2)

Guidance literature:

In benzene; at 80 ℃; for 4h;

DOI:10.1021/jo001150v

Reference yield:

9,9'-bis(trimethylsilyl)fluorene (7351-45-3) → 2,7-bis(trimethylsilyl)-9-fluorenylmethyl carbanilate (136453-40-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 74.4 percent / N-bromosuccinimide; 48percent HBr / acetic acid / 6 h

2: 70.9 percent / Na / toluene

3: 93.8 percent / KOH / aq. ethanol / 2 h / Heating

4: 50.16 percent / n-BuLi / diethyl ether / 0.5 h / 20 °C

5: 87.13 percent / benzene / 4 h / 80 °C

With potassium hydroxide; N-Bromosuccinimide; n-butyllithium; sodium; In diethyl ether; ethanol; acetic acid; toluene; benzene;

DOI:10.1021/jo001150v

Reference yield:

2,7-bis(trimethylsilyl)fluorene (136453-57-1) → 2,7-bis(trimethylsilyl)-9-fluorenylmethyl carbanilate (136453-40-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 50.16 percent / n-BuLi / diethyl ether / 0.5 h / 20 °C

2: 87.13 percent / benzene / 4 h / 80 °C

With n-butyllithium; In diethyl ether; benzene;

DOI:10.1021/jo001150v

upstream raw materials:

phenyl isocyanate

2,7-bis(trimethylsilyl)fluorene-9-methanol

9,9'-bis(trimethylsilyl)fluorene

2,7-bis(trimethylsilyl)fluorene