(1R,3R,4R,5S,8R)-1-(biphenyl-4-yl)-5-isopropyl-8-methyl-3-spiro[2.5]octan-4,5-diole

Base Information

Chemical Name:(1R,3R,4R,5S,8R)-1-(biphenyl-4-yl)-5-isopropyl-8-methyl-3-spiro[2.5]octan-4,5-diole
CAS No.:1383783-19-4
Molecular Formula:C₂₄H₃₀O₂
Molecular Weight:350.501
Hs Code.:

Synonyms:(1R,3R,4R,5S,8R)-1-(biphenyl-4-yl)-5-isopropyl-8-methyl-3-spiro[2.5]octan-4,5-diole

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Chemical Property of (1R,3R,4R,5S,8R)-1-(biphenyl-4-yl)-5-isopropyl-8-methyl-3-spiro[2.5]octan-4,5-diole

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Technology Process of (1R,3R,4R,5S,8R)-1-(biphenyl-4-yl)-5-isopropyl-8-methyl-3-spiro[2.5]octan-4,5-diole

There total 2 articles about (1R,3R,4R,5S,8R)-1-(biphenyl-4-yl)-5-isopropyl-8-methyl-3-spiro[2.5]octan-4,5-diole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 909031-42-1
(1R,5S,8R,3R)-1-(biphenyl-4-yl)-5-isopropyl-5-hydroxy-8-methyl-3-spiro[2.5]octan-4-one

: 1383783-19-4
(1R,3R,4R,5S,8R)-1-(biphenyl-4-yl)-5-isopropyl-8-methyl-3-spiro[2.5]octan-4,5-diole

Guidance literature:: With sodium tetrahydroborate; In isopropyl alcohol; at 20 ℃;
DOI:10.1016/j.molstruc.2012.03.052

Reference yield:

: 909031-41-0
C₂₄H₂₈O

: 1383783-19-4
(1R,3R,4R,5S,8R)-1-(biphenyl-4-yl)-5-isopropyl-8-methyl-3-spiro[2.5]octan-4,5-diole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / 24 h / 20 °C

2: sodium tetrahydroborate / isopropyl alcohol / 20 °C

With sodium tetrahydroborate; sodium hydroxide; In isopropyl alcohol;
DOI:10.1016/j.molstruc.2012.03.052