methyl 4-methoxy-<2,6-2H2>benzoate

Base Information

• Chemical Name: methyl 4-methoxy-<2,6-2H2>benzoate
• CAS No.: 152404-50-7
• Molecular Formula: C₉H₁₀O₃
• Molecular Weight: 168.161
• Mol file: 152404-50-7.mol

Synonyms:methyl 4-methoxy-<2,6-2H2>benzoate

Chemical Property of methyl 4-methoxy-<2,6-2H2>benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4-methoxy-<2,6-2H2>benzoate

There total 2 articles about methyl 4-methoxy-<2,6-2H2>benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-methoxybenzoate (121-98-2) → methyl 4-methoxy-<2,6-2H2>benzoate (152404-50-7)

Guidance literature:

With F₆P^(1-)*C₄₇H₇₀IrN₂P⁽¹⁺⁾; deuterium; In dichloromethane; at 25 ℃; for 1h; under 760.051 Torr; chemoselective reaction;

DOI:10.3390/molecules200711676

Reference yield:

methyl 3,5-dibromo-4-methoxy-<2,6-2H2>benzoate (152404-49-4) → methyl 4-methoxy-<2,6-2H2>benzoate (152404-50-7)

Guidance literature:

With acetic acid; zinc; for 72h; Heating;

DOI:10.1021/ja00079a009

Reference yield:

methyl 4-methoxy-<2,6-2H2>benzoate (152404-50-7) → 4-hydroxy-<2,6-2H2>benzoic acid

Guidance literature:

Multi-step reaction with 2 steps

1: 10percent aq. NaOH / 1 h / Heating

2: BBr₃ / CH₂Cl₂ / 8 h / Ambient temperature

With sodium hydroxide; boron tribromide; In dichloromethane;

DOI:10.1021/ja00079a009

upstream raw materials:

methyl 3,5-dibromo-4-methoxy-<2,6-2H2>benzoate

methyl 4-methoxybenzoate

Downstream raw materials:

4-methoxylbenzoic acid-2,6-d₂