4-Chloro-2,5-difluoropyridine

Base Information

Chemical Name:4-Chloro-2,5-difluoropyridine
CAS No.:851386-40-8
Molecular Formula:C5H2 Cl F2 N
Molecular Weight:149.527
Hs Code.:2933399090
European Community (EC) Number:865-401-2
DSSTox Substance ID:DTXSID40456840
Wikidata:Q82279417
Mol file:851386-40-8.mol

Synonyms:4-CHLORO-2,5-DIFLUOROPYRIDINE;851386-40-8;2,5-Difluoro-4-chloropyridine;Pyridine, 4-chloro-2,5-difluoro-;MFCD09031178;SCHEMBL15817436;AMY6615;DTXSID40456840;AKOS005258324;AS-59736;Benzoicacid,4-butoxy-,4-ethoxyphenylester;SY009809;CS-0044528;FT-0681745;C76731;EN300-198567;A863687

Suppliers and Price of 4-Chloro-2,5-difluoropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-2,5-difluoropyridine
500mg
$ 310.00

Matrix Scientific
4-Chloro-2,5-difluoropyridine 88%
1g
$ 345.00

Crysdot
4-Chloro-2,5-difluoropyridine 95+%
250mg
$ 138.00

Crysdot
4-Chloro-2,5-difluoropyridine 95+%
100mg
$ 86.00

Crysdot
4-Chloro-2,5-difluoropyridine 95+%
1g
$ 330.00

Chemenu
4-chloro-2,5-difluoropyridine 95%
1g
$ 327.00

American Custom Chemicals Corporation
4-CHLORO-2,5-DIFLUOROPYRIDINE 95.00%
5MG
$ 502.72

Ambeed
4-Chloro-2,5-difluoropyridine 95+%
1g
$ 180.00

Ambeed
4-Chloro-2,5-difluoropyridine 95+%
250mg
$ 72.00

Ambeed
4-Chloro-2,5-difluoropyridine 95+%
100mg
$ 46.00

Total 17 raw suppliers

Chemical Property of 4-Chloro-2,5-difluoropyridine

Chemical Property:

Vapor Pressure:5.75mmHg at 25°C
Refractive Index:1.479
Boiling Point:146.9°C at 760 mmHg
Flash Point:42.6°C
PSA：12.89000
Density:1.451g/cm³
LogP:2.01320
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:148.9843831
Heavy Atom Count:9
Complexity:101

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-2,5-difluoropyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CN=C1F)F)Cl

Technology Process of 4-Chloro-2,5-difluoropyridine

There total 1 articles about 4-Chloro-2,5-difluoropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 84476-99-3
2,5-difluoropyridine

: 851386-40-8
4-chloro-2,5-difluoropyridine

Guidance literature:: 2,5-difluoropyridine; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; tert-butyl methyl ether; at -78 ℃; for 1h;

With 1,1,2-Trichloro-1,2,2-trifluoroethane; In tetrahydrofuran; hexane; tert-butyl methyl ether; at -75 ℃; for 2h; Heating;

Reference yield: 83.0%

: 851386-40-8
4-chloro-2,5-difluoropyridine

: 69807-91-6
2-(3,5-bis-trifluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

: C₁₃H₅F₈N

Guidance literature:: With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; water; at 110 ℃; for 1.5h;

Reference yield: 71.0%

: 851386-40-8
4-chloro-2,5-difluoropyridine

: 3-trifluoromethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

: C₁₃H₅F₅N₂

Guidance literature:: With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; water; at 110 ℃; for 4h;