6-(4-Trifluoromethoxyphenyl)-nicotinic acid

Base Information

Chemical Name:6-(4-Trifluoromethoxyphenyl)-nicotinic acid
CAS No.:851266-73-4
Molecular Formula:C14H10 F3 N O3
Molecular Weight:297.234
Hs Code.:2933399990
Mol file:851266-73-4.mol

Synonyms:methyl 6-[4-(trifluoromethoxy)phenyl]nicotinate;6-(4-(Trifluoromethoxy)phenyl)nicotinic acid;

Suppliers and Price of 6-(4-Trifluoromethoxyphenyl)-nicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-(4-(TRIFLUOROMETHOXY)PHENYL)NICOTINIC ACID 95.00%
1G
$ 567.00

Alichem
Methyl6-(4-(trifluoromethoxy)phenyl)nicotinate
500mg
$ 815.00

Alichem
Methyl6-(4-(trifluoromethoxy)phenyl)nicotinate
250mg
$ 475.20

Total 6 raw suppliers

Chemical Property of 6-(4-Trifluoromethoxyphenyl)-nicotinic acid

Chemical Property:

PSA：59.42000
LogP:3.34540

Purity/Quality:

98%min ^*data from raw suppliers

6-(4-(TRIFLUOROMETHOXY)PHENYL)NICOTINIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-(4-Trifluoromethoxyphenyl)-nicotinic acid

There total 1 articles about 6-(4-Trifluoromethoxyphenyl)-nicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 73781-91-6
6-Chloronicotinic acid methyl ester

: 139301-27-2
4-trifluoromethoxyphenylboronic acid

: 851266-73-4
methyl 6-[4-(trifluoromethoxy)phenyl]nicotinate

Guidance literature:: 6-Chloronicotinic acid methyl ester; 4-trifluoromethoxyphenylboronic acid; With 1,2-dimethoxyethane; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; at 80 ℃; for 16h;

With water; In 1,2-dimethoxyethane;

Reference yield: 91.0%

: 851266-73-4
methyl 6-[4-(trifluoromethoxy)phenyl]nicotinate

: 851266-74-5
6-[4-(trifluoromethoxy)phenyl]nicotinic acid

Guidance literature:: methyl 6-[4-(trifluoromethoxy)phenyl]nicotinate; With potassium hydroxide; In methanol; water; at 40 ℃;

With hydrogenchloride; water; pH=2;

With diethyl ether;