(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropionylamino)-3-phenylpropionylamino]-4-methylpentanoic acid methyl ester

Base Information

Chemical Name:(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropionylamino)-3-phenylpropionylamino]-4-methylpentanoic acid methyl ester
CAS No.:1235998-13-6
Molecular Formula:C₂₄H₃₇N₃O₇
Molecular Weight:479.574
Hs Code.:

Synonyms:(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropionylamino)-3-phenylpropionylamino]-4-methylpentanoic acid methyl ester

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Chemical Property of (S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropionylamino)-3-phenylpropionylamino]-4-methylpentanoic acid methyl ester

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Technology Process of (S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropionylamino)-3-phenylpropionylamino]-4-methylpentanoic acid methyl ester

There total 1 articles about (S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropionylamino)-3-phenylpropionylamino]-4-methylpentanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 7517-19-3
methyl (L)-leucinate hydrochloride

: 130380-69-7
(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropionylamino)-3-phenylpropionic acid

: 1235998-13-6
(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropionylamino)-3-phenylpropionylamino]-4-methylpentanoic acid methyl ester

Guidance literature:: With triethylamine; HATU; In dichloromethane; Inert atmosphere;
DOI:10.1021/ja102733a

Reference yield: 100.0%

: 1235998-13-6
(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropionylamino)-3-phenylpropionylamino]-4-methylpentanoic acid methyl ester

: 1235998-14-7
(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropionylamino)-3-phenylpropionylamino]-4-methylpentanoic acid

Guidance literature:: (S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropionylamino)-3-phenylpropionylamino]-4-methylpentanoic acid methyl ester; With lithium hydroxide; In tetrahydrofuran; water; at 0 ℃; for 18h;

With hydrogenchloride; In water; at 0 ℃; pH=4;
DOI:10.1021/ja102733a