Glycinyl m-(trifluoromethyl)cinnamate

Base Information

Chemical Name:Glycinyl m-(trifluoromethyl)cinnamate
CAS No.:1029092-60-1
Molecular Formula:C₁₂H₁₀F₃NO₃
Molecular Weight:273.212
Hs Code.:
UNII:M4SJ278R3C
Wikidata:Q27283491

Synonyms:Glycinyl m-(trifluoromethyl)cinnamate;Cinacalcet (m7-gly);UNII-M4SJ278R3C;M4SJ278R3C;1029092-60-1;Glycine, N-(1-oxo-3-(3-(trifluoromethyl)phenyl)-2-propen-1-yl)-;2-[[(E)-3-[3-(trifluoromethyl)phenyl]prop-2-enoyl]amino]acetic acid;SCHEMBL16071013;JYMGWJYSVGDUQH-SNAWJCMRSA-N;HMS1512K15;AKOS002112644;NCGC00320022-01;AB01316561-02;SR-01000146453;SR-01000146453-1;Q27283491

Suppliers and Price of Glycinyl m-(trifluoromethyl)cinnamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Glycinyl m-(trifluoromethyl)cinnamate

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:273.06127767
Heavy Atom Count:19
Complexity:366

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C(F)(F)F)C=CC(=O)NCC(=O)O
Isomeric SMILES:C1=CC(=CC(=C1)C(F)(F)F)/C=C/C(=O)NCC(=O)O

Technology Process of Glycinyl m-(trifluoromethyl)cinnamate

There total 2 articles about Glycinyl m-(trifluoromethyl)cinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₆H₁₈F₃NO₃

: 1029092-60-1
M₇-Gly

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 779-89-5,67801-07-4
3-(trifluoromethyl)cinnamic acid

: 1029092-60-1
M₇-Gly

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / tetrahydrofuran; N,N-dimethyl-formamide / 20 °C

2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

Reference yield: 62.0%

: 1029092-60-1
M₇-Gly

: 3867-92-3
methyl 2-amino-2-deoxy-β-D-glucopyranoside

: methyl 2-deoxy-2-{[({(2E)-3-[3-(trifluoromethyl)phenyl]prop-2-enoyl}amino)acetyl]amino}-β-D-glucopyranoside

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃;