(1S,2S)-N-<(1S)-Methylbenzyl>-1-<(1,3-benzodioxol-5-yl)ethynyl>-2-aminocyclopentanol

Base Information

Chemical Name:(1S,2S)-N-<(1S)-Methylbenzyl>-1-<(1,3-benzodioxol-5-yl)ethynyl>-2-aminocyclopentanol
CAS No.:150357-75-8
Molecular Formula:C₂₂H₂₃NO₃
Molecular Weight:349.43
Hs Code.:

Synonyms:(1S,2S)-N-<(1S)-Methylbenzyl>-1-<(1,3-benzodioxol-5-yl)ethynyl>-2-aminocyclopentanol

Suppliers and Price of (1S,2S)-N-<(1S)-Methylbenzyl>-1-<(1,3-benzodioxol-5-yl)ethynyl>-2-aminocyclopentanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2S)-N-<(1S)-Methylbenzyl>-1-<(1,3-benzodioxol-5-yl)ethynyl>-2-aminocyclopentanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2S)-N-<(1S)-Methylbenzyl>-1-<(1,3-benzodioxol-5-yl)ethynyl>-2-aminocyclopentanol

There total 5 articles about (1S,2S)-N-<(1S)-Methylbenzyl>-1-<(1,3-benzodioxol-5-yl)ethynyl>-2-aminocyclopentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 150357-74-7
(1S,2S)-N-<(1S)-Methylbenzyl>-N-(cyanomethyl)-1-<(1,3-benzodioxol-5-yl)ethynyl>-2-aminocyclopentanol

: 150357-75-8
(1S,2S)-N-<(1S)-Methylbenzyl>-1-<(1,3-benzodioxol-5-yl)ethynyl>-2-aminocyclopentanol

Guidance literature:: With silver nitrate; In ethanol; 1.) 23 deg C, 2 h, sonication, 48 h, 2.) HNO₃, sonication, 72 h;
DOI:10.1021/jo00069a032

Reference yield:

: 57134-53-9
3,4-methylenedioxyphenylethyne

: 150357-75-8
(1S,2S)-N-<(1S)-Methylbenzyl>-1-<(1,3-benzodioxol-5-yl)ethynyl>-2-aminocyclopentanol

Guidance literature:: Multi-step reaction with 2 steps

1: 15 percent / CeCl₃, n-BuLi / tetrahydrofuran / 1.) -78 deg C, 30 min, 2.) -78 deg C, 2 h

2: 95 percent / AgNO₃ / aq. ethanol / 1.) 23 deg C, 2 h, sonication, 48 h, 2.) HNO₃, sonication, 72 h

With n-butyllithium; cerium(III) chloride; silver nitrate; In tetrahydrofuran; ethanol;
DOI:10.1021/jo00069a032

Reference yield:

: 120-57-0,30024-74-9
piperonal

: 150357-75-8
(1S,2S)-N-<(1S)-Methylbenzyl>-1-<(1,3-benzodioxol-5-yl)ethynyl>-2-aminocyclopentanol

Guidance literature:: Multi-step reaction with 4 steps

1: Zn, PPh₃ / CH₂Cl₂ / 5 h / 23 °C

2: n-BuLi / tetrahydrofuran / 1.) -78 deg C, 1 h, 2.) -78 deg C -> 23 deg C, 30 min, 3.) 23 deg C, 1 h

3: 15 percent / CeCl₃, n-BuLi / tetrahydrofuran / 1.) -78 deg C, 30 min, 2.) -78 deg C, 2 h

4: 95 percent / AgNO₃ / aq. ethanol / 1.) 23 deg C, 2 h, sonication, 48 h, 2.) HNO₃, sonication, 72 h

With n-butyllithium; cerium(III) chloride; silver nitrate; triphenylphosphine; zinc; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/jo00069a032