4-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-yl)thio]acetylhydrazine

Base Information

• Chemical Name: 4-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-yl)thio]acetylhydrazine
• CAS No.: 649758-53-2
• Molecular Formula: C₁₃H₁₂N₆OS
• Molecular Weight: 300.344
• Mol file: 649758-53-2.mol

Synonyms:4-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-yl)thio]acetylhydrazine

Chemical Property of 4-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-yl)thio]acetylhydrazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-yl)thio]acetylhydrazine

There total 4 articles about 4-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-yl)thio]acetylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-(ethoxycarbonylmethyl)thio-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (335223-43-3) → 4-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-yl)thio]acetylhydrazine (649758-53-2)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h; Heating;

DOI:10.1080/10426500307825

Reference yield:

4-chloro-1-(phenyl)-1H-pyrazolo[3,4-d]pyrimidine (5334-48-5) → 4-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-yl)thio]acetylhydrazine (649758-53-2)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol / 7 h / Heating

2: 84 percent / K₂CO₃ / acetone / 24 h / Heating

3: 91 percent / hydrazine hydrate / ethanol / 3 h / Heating

With potassium carbonate; hydrazine hydrate; In ethanol; acetone;

DOI:10.1080/10426500307825

Reference yield:

4-mercapto-1-phenyl-1,5-dihydro-1H-pyrazolo[3,4-d]pyrimidine (6014-07-9) → 4-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4-yl)thio]acetylhydrazine (649758-53-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / K₂CO₃ / acetone / 24 h / Heating

2: 91 percent / hydrazine hydrate / ethanol / 3 h / Heating

With potassium carbonate; hydrazine hydrate; In ethanol; acetone;

DOI:10.1080/10426500307825

upstream raw materials:

4-(ethoxycarbonylmethyl)thio-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine

4-chloro-1-(phenyl)-1H-pyrazolo[3,4-d]pyrimidine

4-mercapto-1-phenyl-1,5-dihydro-1H-pyrazolo[3,4-d]pyrimidine