trans-9,9a-dihydro-6,7-dimethoxy-9-(phenylmethyl)-3H-pyrrolo<1,2-a>indole-9-carbonitrile 4-oxide

Base Information

Chemical Name:trans-9,9a-dihydro-6,7-dimethoxy-9-(phenylmethyl)-3H-pyrrolo<1,2-a>indole-9-carbonitrile 4-oxide
CAS No.:97655-33-9
Molecular Formula:C₂₁H₂₀N₂O₃
Molecular Weight:348.401
Hs Code.:

Synonyms:trans-9,9a-dihydro-6,7-dimethoxy-9-(phenylmethyl)-3H-pyrrolo<1,2-a>indole-9-carbonitrile 4-oxide

Suppliers and Price of trans-9,9a-dihydro-6,7-dimethoxy-9-(phenylmethyl)-3H-pyrrolo<1,2-a>indole-9-carbonitrile 4-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of trans-9,9a-dihydro-6,7-dimethoxy-9-(phenylmethyl)-3H-pyrrolo<1,2-a>indole-9-carbonitrile 4-oxide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of trans-9,9a-dihydro-6,7-dimethoxy-9-(phenylmethyl)-3H-pyrrolo<1,2-a>indole-9-carbonitrile 4-oxide

There total 4 articles about trans-9,9a-dihydro-6,7-dimethoxy-9-(phenylmethyl)-3H-pyrrolo<1,2-a>indole-9-carbonitrile 4-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 97655-31-7
trans-9,9a-dihydro-6,7-dimethoxy-9-(phenylmethyl)-3H-pyrrolo<1,2-a>indole-9-carbonitrile

: 97655-33-9
trans-9,9a-dihydro-6,7-dimethoxy-9-(phenylmethyl)-3H-pyrrolo<1,2-a>indole-9-carbonitrile 4-oxide

Guidance literature:: With dihydrogen peroxide; In acetic acid; for 48h; Ambient temperature;
DOI:10.1021/jo00220a024

Reference yield:

: 50546-80-0
(2-amino-4,5-dimethoxy-phenyl)-acetonitrile

: 97655-33-9
trans-9,9a-dihydro-6,7-dimethoxy-9-(phenylmethyl)-3H-pyrrolo<1,2-a>indole-9-carbonitrile 4-oxide

Guidance literature:: Multi-step reaction with 4 steps

1: 86 percent / ethyldiisopropylamine / KI / toluene / 4 h / 110 °C

2: 1.) NaOH / 1.) ethanol, 15 min, 2.) ethanol, RT, 15 h

3: zinc chloride / acetonitrile / 2.75 h / 81 °C

4: 100 percent / 30percent hydrogen peroxide / acetic acid / 48 h / Ambient temperature

With sodium hydroxide; dihydrogen peroxide; N-ethyl-N,N-diisopropylamine; zinc(II) chloride; potassium iodide; In acetic acid; toluene; acetonitrile;
DOI:10.1021/jo00220a024

Reference yield:

: 97655-16-8
4,5-dimethoxy-2-(2,5-dihydro-1H-pyrrol-1-yl)benzeneacetonitrile

: 97655-33-9
trans-9,9a-dihydro-6,7-dimethoxy-9-(phenylmethyl)-3H-pyrrolo<1,2-a>indole-9-carbonitrile 4-oxide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaOH / 1.) ethanol, 15 min, 2.) ethanol, RT, 15 h

2: zinc chloride / acetonitrile / 2.75 h / 81 °C

3: 100 percent / 30percent hydrogen peroxide / acetic acid / 48 h / Ambient temperature

With sodium hydroxide; dihydrogen peroxide; zinc(II) chloride; In acetic acid; acetonitrile;
DOI:10.1021/jo00220a024