Technology Process of 3,5,7-tri-O-benzyl-1,4,6-trideoxy-4,6-di-C-methyl-keto-L-ido-2-heptulose
There total 27 articles about 3,5,7-tri-O-benzyl-1,4,6-trideoxy-4,6-di-C-methyl-keto-L-ido-2-heptulose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
molecular sieve; pyridinium chlorochromate;
In
dichloromethane;
for 5.5h;
Ambient temperature;
DOI:10.1016/0008-6215(82)84027-5
- Guidance literature:
-
Multi-step reaction with 13 steps
1: 24.1 g / anhydrous FeCl3 / 2.5 h / Ambient temperature
2: 90percent aq. AcOH / 1.5 h / 60 °C
3: 85 percent / DMAP / pyridine / 0.42 h / 0 °C
4: 86 percent / Jones reagent / acetone / 1.5 h / Ambient temperature
5: 52 percent / 4M methylsulfinylmethanide anion/Me2SO / diethyl ether / 0.25 h / Ambient temperature
6: 95 percent / 1M aq. NaOH / methanol / 0.25 h
7: 60 percent / 70percent aq. TFA / 2 h / Ambient temperature
8: 80 percent / H2 / (Ph3P)3RhCl / benzene / 3 h / Ambient temperature
9: 95 percent / BF3*Et2O / 1 h / Ambient temperature
10: 74 percent / NaH / dimethylformamide / 18 h / Ambient temperature
11: 88 percent / HgO, HgCl2 / acetone; H2O / 0.75 h / Ambient temperature
12: 90 percent / Mg / diethyl ether / 1 h / Ambient temperature
13: 86 percent / PCC, molecular sieves / CH2Cl2 / 5.5 h / Ambient temperature
With
dmap; sodium hydroxide; jones reagent; molecular sieve; dimethyl sulfoxide; deprotonated form; boron trifluoride diethyl etherate; hydrogen; iron(III) chloride; sodium hydride; magnesium; acetic acid; dimethyl sulfoxide; pyridinium chlorochromate; trifluoroacetic acid; mercury dichloride; mercury(II) oxide;
Wilkinson's catalyst;
In
pyridine; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; acetone; benzene;
DOI:10.1016/0008-6215(82)84027-5
- Guidance literature:
-
Multi-step reaction with 11 steps
1: 85 percent / DMAP / pyridine / 0.42 h / 0 °C
2: 86 percent / Jones reagent / acetone / 1.5 h / Ambient temperature
3: 52 percent / 4M methylsulfinylmethanide anion/Me2SO / diethyl ether / 0.25 h / Ambient temperature
4: 95 percent / 1M aq. NaOH / methanol / 0.25 h
5: 60 percent / 70percent aq. TFA / 2 h / Ambient temperature
6: 80 percent / H2 / (Ph3P)3RhCl / benzene / 3 h / Ambient temperature
7: 95 percent / BF3*Et2O / 1 h / Ambient temperature
8: 74 percent / NaH / dimethylformamide / 18 h / Ambient temperature
9: 88 percent / HgO, HgCl2 / acetone; H2O / 0.75 h / Ambient temperature
10: 90 percent / Mg / diethyl ether / 1 h / Ambient temperature
11: 86 percent / PCC, molecular sieves / CH2Cl2 / 5.5 h / Ambient temperature
With
dmap; sodium hydroxide; jones reagent; molecular sieve; dimethyl sulfoxide; deprotonated form; boron trifluoride diethyl etherate; hydrogen; sodium hydride; magnesium; dimethyl sulfoxide; pyridinium chlorochromate; trifluoroacetic acid; mercury dichloride; mercury(II) oxide;
Wilkinson's catalyst;
In
pyridine; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; acetone; benzene;
DOI:10.1016/0008-6215(82)84027-5
