trans-N-benzyl-N-2-buten-1-yl-2-(4-methylphenyl)sulfonylaminoacetamide

Base Information

• Chemical Name: trans-N-benzyl-N-2-buten-1-yl-2-(4-methylphenyl)sulfonylaminoacetamide
• CAS No.: 1361843-97-1
• Molecular Formula: C₂₀H₂₄N₂O₃S
• Molecular Weight: 372.488
• Mol file: 1361843-97-1.mol

Synonyms:trans-N-benzyl-N-2-buten-1-yl-2-(4-methylphenyl)sulfonylaminoacetamide

Chemical Property of trans-N-benzyl-N-2-buten-1-yl-2-(4-methylphenyl)sulfonylaminoacetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-N-benzyl-N-2-buten-1-yl-2-(4-methylphenyl)sulfonylaminoacetamide

There total 2 articles about trans-N-benzyl-N-2-buten-1-yl-2-(4-methylphenyl)sulfonylaminoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

benzyl crotyl amine (107733-62-0) + N-Tosylglycine (1080-44-0) → trans-N-benzyl-N-2-buten-1-yl-2-(4-methylphenyl)sulfonylaminoacetamide (1361843-97-1)

Guidance literature:

N-Tosylglycine; With thionyl chloride; for 2h; Inert atmosphere; Reflux;

benzyl crotyl amine; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1002/adsc.201600813

Reference yield:

N-crotylbenzylcarbamate (4393-07-1) + N-Tosylglycine (1080-44-0) → cis-N-benzyl-N-2-buten-1-yl-2-(4-methylphenyl)sulfonylaminoacetamide + trans-N-benzyl-N-2-buten-1-yl-2-(4-methylphenyl)sulfonylaminoacetamide (1361843-97-1)

Guidance literature:

N-Tosylglycine; With thionyl chloride; In toluene; at 60 ℃; for 3h; Inert atmosphere;

N-crotylbenzylcarbamate; With triethylamine; In dichloromethane; for 48h;

DOI:10.1021/ol300030w

Reference yield: 85.0%

trans-N-benzyl-N-2-buten-1-yl-2-(4-methylphenyl)sulfonylaminoacetamide (1361843-97-1) → (E)-3-benzyl-2-(prop-1-en-1-yl)-1-tosylimidazolidin-4-one

Guidance literature:

With sodium acetate; tetra(n-butyl)ammonium hydrogensulfate; palladium diacetate; bis-[(trifluoroacetoxy)iodo]benzene; In 1,2-dichloro-ethane; at 80 ℃; Reagent/catalyst; Temperature; Catalytic behavior; Inert atmosphere; Reflux;

DOI:10.1002/adsc.201600813

upstream raw materials:

N-crotylbenzylcarbamate

N-Tosylglycine

benzyl crotyl amine