C₄₄H₇₆O₂Si

Base Information

• Chemical Name: C₄₄H₇₆O₂Si
• CAS No.: 1454597-85-3
• Molecular Formula: C₄₄H₇₆O₂Si
• Molecular Weight: 665.172
• Mol file: 1454597-85-3.mol

Synonyms:C₄₄H₇₆O₂Si

Chemical Property of C₄₄H₇₆O₂Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₄H₇₆O₂Si

There total 15 articles about C₄₄H₇₆O₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C50H90O2Si2 (1454597-83-1) → C44H76O2Si (1454597-85-3)

Guidance literature:

With tetra-N-butylammonium tribromide; In tetrahydrofuran; methanol; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/anie.201303776

Reference yield:

octadec-1-yn-3-ol (146333-96-2) → C44H76O2Si (1454597-85-3)

Guidance literature:

Multi-step reaction with 10 steps

1.1: Candita antarctica lipase B / hexane / 3 h / 20 °C / Inert atmosphere; Resolution of racemate; Enzymatic reaction

2.1: methyllithium / tetrahydrofuran / 0.67 h / -20 - 20 °C / Inert atmosphere

2.2: 1 h / 40 °C / Inert atmosphere

2.3: 0.25 h / 0 °C / Inert atmosphere

3.1: tert.-butyl lithium / diethyl ether; pentane / 0.17 h / -78 °C / Inert atmosphere

3.2: 2 h / -78 - 20 °C / Inert atmosphere

3.3: 2 h / 20 °C / Darkness

4.1: pyridine / dichloromethane / 1 h / 0 °C / Inert atmosphere

5.1: tetra-N-butylammonium tribromide / methanol / 4 h / 20 °C / Inert atmosphere

6.1: hydrogen; [Ir(cod)(SIMes)(Pyr)]⁺PF₆^- / dichloromethane / 18 h / 20 °C / 67506.8 Torr / Autoclave

7.1: 1H-imidazole; dmap / dichloromethane / 0.5 h / 20 °C / Inert atmosphere

8.1: potassium carbonate / methanol / 6 h / 60 °C / Inert atmosphere

9.1: 2,6-dimethylpyridine / dichloromethane / 5 h / 0 °C / Inert atmosphere

10.1: tetra-N-butylammonium tribromide / methanol; tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

With pyridine; 1H-imidazole; 2,6-dimethylpyridine; dmap; Candita antarctica lipase B; [Ir(cod)(SIMes)(Pyr)]⁺PF₆^-; methyllithium; hydrogen; tert.-butyl lithium; tetra-N-butylammonium tribromide; potassium carbonate; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; pentane;

DOI:10.1002/anie.201303776

Reference yield:

C16H35IOSi (1283733-08-3) → C44H76O2Si (1454597-85-3)

Guidance literature:

Multi-step reaction with 8 steps

1.1: tert.-butyl lithium / diethyl ether; pentane / 0.17 h / -78 °C / Inert atmosphere

1.2: 2 h / -78 - 20 °C / Inert atmosphere

1.3: 2 h / 20 °C / Darkness

2.1: pyridine / dichloromethane / 1 h / 0 °C / Inert atmosphere

3.1: tetra-N-butylammonium tribromide / methanol / 4 h / 20 °C / Inert atmosphere

4.1: hydrogen; [Ir(cod)(SIMes)(Pyr)]⁺PF₆^- / dichloromethane / 18 h / 20 °C / 67506.8 Torr / Autoclave

5.1: 1H-imidazole; dmap / dichloromethane / 0.5 h / 20 °C / Inert atmosphere

6.1: potassium carbonate / methanol / 6 h / 60 °C / Inert atmosphere

7.1: 2,6-dimethylpyridine / dichloromethane / 5 h / 0 °C / Inert atmosphere

8.1: tetra-N-butylammonium tribromide / methanol; tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

With pyridine; 1H-imidazole; 2,6-dimethylpyridine; dmap; [Ir(cod)(SIMes)(Pyr)]⁺PF₆^-; hydrogen; tert.-butyl lithium; tetra-N-butylammonium tribromide; potassium carbonate; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; pentane;

DOI:10.1002/anie.201303776

upstream raw materials:

C₁₈H₃₅IO

octadec-1-yn-3-ol

C₁₆H₃₆O₂Si

C₁₆H₃₅IOSi

Downstream raw materials:

C₄₄H₇₅IOSi