6-HYDROXY-2-NAPHTHOIC HYDRAZIDE

Base Information

• Chemical Name: 6-HYDROXY-2-NAPHTHOIC HYDRAZIDE
• CAS No.: 849421-24-5
• Molecular Formula: C11H10 N2 O2
• Molecular Weight: 202.21
• Hs Code.: 2928000090
• Mol file: 849421-24-5.mol

Synonyms:6-HYDROXY-2-NAPHTHOIC HYDRAZIDE

Chemical Property of 6-HYDROXY-2-NAPHTHOIC HYDRAZIDE

Chemical Property:

• PSA: 75.35000
• LogP: 2.24010

Purity/Quality:

6-Hydroxy-2-naphthohydrazide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-HYDROXY-2-NAPHTHOIC HYDRAZIDE

There total 3 articles about 6-HYDROXY-2-NAPHTHOIC HYDRAZIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

ethyl 6-hydroxy-2-naphthoate (17295-12-4) → 6-hydroxy-naphthalene-2-carboxylic acid hydrazide (849421-24-5)

Guidance literature:

With hydrazine hydrate; Reflux;

DOI:10.1016/j.saa.2018.11.031

Reference yield:

methyl 6-hydroxynaphthalene-2-carboxylate (17295-11-3) → 6-hydroxy-naphthalene-2-carboxylic acid hydrazide (849421-24-5)

Guidance literature:

With hydrazine; In water; butan-1-ol; at 20 - 100 ℃; for 49h;

Reference yield:

→ 6-hydroxy-naphthalene-2-carboxylic acid hydrazide (849421-24-5)

Guidance literature:

With hydrazine hydrate;

upstream raw materials:

methyl 6-hydroxynaphthalene-2-carboxylate

ethyl 6-hydroxy-2-naphthoate

Downstream raw materials:

6-hydroxy-naphthalene-2-carboxylic acid (3,5-dibromo-2,4-dihydroxy-benzylidene)-hydrazide

Refernces

• 1、 Li, Na-Na,Ma, Yu-Qing,Sun, Xue-Jiao,Li, Ming-Qiang,Zeng, Shuang,Xing, Zhi-Yong,Li, Jin-Long. "A dual-function probe based on naphthalene for fluorescent turn-on recognition of Cu2+ and colorimetric detection of Fe3+ in neat H2O". . p. 266 - 274. Retrieved 2018/11/25.
• 2、 -. "Hydroxynaphthoic acid hydrazide compounds and method for preparing the same". Page/Page column 6. . Retrieved 2008/06/13.