dimethyl 2-amino-5-iodoterephthalate

Base Information

• Chemical Name: dimethyl 2-amino-5-iodoterephthalate
• CAS No.: 1357367-02-2
• Molecular Formula: C₁₀H₁₀INO₄
• Molecular Weight: 335.098
• Mol file: 1357367-02-2.mol

Synonyms:dimethyl 2-amino-5-iodoterephthalate

Chemical Property of dimethyl 2-amino-5-iodoterephthalate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of dimethyl 2-amino-5-iodoterephthalate

There total 1 articles about dimethyl 2-amino-5-iodoterephthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

dimethyl aminoterephthalate (5372-81-6) → dimethyl 2-amino-5-iodoterephthalate (1357367-02-2)

Guidance literature:

With N-iodo-succinimide; In methanol; dichloromethane; for 16h; Darkness; Reflux;

DOI:10.1002/ejoc.201801864

Reference yield: 97.0%

trimethylsilylazide (4648-54-8) + dimethyl 2-amino-5-iodoterephthalate (1357367-02-2) → dimethyl 2-azido-5-iodoterephthalate

Guidance literature:

dimethyl 2-amino-5-iodoterephthalate; With tert.-butylnitrite; In acetonitrile; for 0.5h; Cooling with ice;

trimethylsilylazide; In acetonitrile; at 20 ℃; for 1h;

DOI:10.1002/ejoc.201801864

Reference yield: 86.0%

dimethyl 2-amino-5-iodoterephthalate (1357367-02-2) → 2-amino-5-iodo-1,4-benzenedicarboxylic acid (1357367-14-6)

Guidance literature:

dimethyl 2-amino-5-iodoterephthalate; With potassium hydroxide; In tetrahydrofuran; water; at 20 ℃;

With hydrogenchloride; In water; at 0 ℃;

DOI:10.1002/anie.201106429

upstream raw materials:

dimethyl aminoterephthalate

Downstream raw materials:

2-amino-5-iodo-1,4-benzenedicarboxylic acid