Quercetin hydrate

Base Information

• Chemical Name: Quercetin hydrate
• CAS No.: 849061-97-8
• Molecular Formula: C15H10 O7 . x H2 O
• Molecular Weight: 320.25
• Hs Code.: 29329990
• European Community (EC) Number: 684-881-2
• ChEMBL ID: CHEMBL1173475
• Mol file: 849061-97-8.mol

Synonyms:Quercetin hydrate;849061-97-8;2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one hydrate;Quercetin (hydrate);1001001-36-0;2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one;hydrate;Quercetin monohydrate;MFCD03847906;2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one xhydrate;SMR000674606;2(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one monohydrate;Quercetin hydrate;Quercetin hydrate, >=95%;MLS001074343;MLS002153851;SCHEMBL1658852;CHEMBL1173475;REGID_for_CID_747934;OKXFBEYCJRMINR-UHFFFAOYSA-N;HMS2234O11;HMS3370H12;REGID_for_CID_16212154;AKOS002318957;BS-23834;D95379;A863909;Quercetin, Pharmaceutical Secondary Standard;Certified Reference Material

Chemical Property of Quercetin hydrate

Chemical Property:

• Vapor Pressure: 1.96E-21mmHg at 25°C
• Melting Point: >300°C
• Boiling Point: 714.6°C at 760 mmHg
• Flash Point: 386°C
• PSA: 140.59000
• LogP: 1.92370
• Solubility.: DMSO: soluble200mg/mL
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 1
• Exact Mass: 320.05321734
• Heavy Atom Count: 23
• Complexity: 488

Purity/Quality:

98%,99%, ^*data from raw suppliers

Quercetin hydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O.O
• Description: Quercetin is an abundant flavonoid that has been isolated from a variety of fruits and vegetables and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) content, and increases total antioxidant capacity in the kidney in a mouse model of cadmium-induced autophagy. It reduces tumor growth, induces apoptosis, and halts the cell cycle at the G1 phase in an HL60 mouse xenograft model when administered at a dose of 120 mg/kg every four days. Quercetin (30 μM) also inhibits histamine release from antigen-stimulated RBL-2H3 cells and decreases the expression of TNF-α, IL-1β, IL-6, and IL-8 induced by PMACI in HMC-1 cells.
• Uses: These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.Quercetin may be used as a pharmaceutical reference standard for the analysis of the analyte in biological samples and pharmaceutical formulations by high performance liquid chromatography (HPLC) and spectrophotometric methods. Quercetin hydrate was used as leishmanicidal flavonol to investigate the inhibition of recombinant arginase from Leishmania amazonensis by quercetin, quercitrin and isoquercitrin.