4-Chloro-2-[3-(trifluoromethyl)phenyl]pyrimidine

Base Information

Chemical Name:4-Chloro-2-[3-(trifluoromethyl)phenyl]pyrimidine
CAS No.:125904-01-0
Molecular Formula:C₁₁H₆ClF₃N₂
Molecular Weight:258.63
Hs Code.:
DSSTox Substance ID:DTXSID801237377

Synonyms:4-CHLORO-2-[3-(TRIFLUOROMETHYL)PHENYL]PYRIMIDINE;DTXSID801237377;AKOS009845034;125904-01-0

Suppliers and Price of 4-Chloro-2-[3-(trifluoromethyl)phenyl]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Chloro-2-[3-(trifluoromethyl)phenyl]pyrimidine

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:258.0171604
Heavy Atom Count:17
Complexity:260

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C(F)(F)F)C2=NC=CC(=N2)Cl

Technology Process of 4-Chloro-2-[3-(trifluoromethyl)phenyl]pyrimidine

There total 3 articles about 4-Chloro-2-[3-(trifluoromethyl)phenyl]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 125903-84-6
2-<3-(trifluoromethyl)phenyl>pyrimidinone

: 125904-01-0
4-chloro-2-<3-(trifluoromethyl)phenyl>pyrimidine

Guidance literature:: With trichlorophosphate; for 3h; Heating;
DOI:10.1021/jm00166a023

Reference yield:

: 1590359-13-9
C₁₂H₉F₃N₂O

: 125904-01-0
4-chloro-2-<3-(trifluoromethyl)phenyl>pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / water

2: trichlorophosphate / toluene

With hydrogenchloride; trichlorophosphate; In water; toluene;
DOI:10.1039/c3ta14876a