3-(bis(4-nitrophenyl)amino)phenol

Base Information

• Chemical Name: 3-(bis(4-nitrophenyl)amino)phenol
• CAS No.: 1396649-85-6
• Molecular Formula: C₁₈H₁₃N₃O₅
• Molecular Weight: 351.318
• Mol file: 1396649-85-6.mol

Synonyms:3-(bis(4-nitrophenyl)amino)phenol

Chemical Property of 3-(bis(4-nitrophenyl)amino)phenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(bis(4-nitrophenyl)amino)phenol

There total 5 articles about 3-(bis(4-nitrophenyl)amino)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(4-nitrophenyl)-λ3-iodanediyl diacetate (19169-99-4) + 3-((4-nitrophenyl)amino)cyclohex-2-en-1-one (36646-76-1) → 3-(bis(4-nitrophenyl)amino)phenol (1396649-85-6)

Guidance literature:

With potassium carbonate; In acetonitrile; at 100 ℃; for 4h; regiospecific reaction; Green chemistry;

DOI:10.1002/adsc.201700004

Reference yield: 30.0%

3-(bis(4-nitrophenyl)amino)-2-iodocyclohex-2-enone (1396650-03-5) → 3-(bis(4-nitrophenyl)amino)phenol (1396649-85-6) + 6-nitro-9-(4-nitrophenyl)-2,3-dihydro-1H-carbazol-4(9H)-one (1396649-65-2)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 0.5h; Microwave irradiation;

DOI:10.1016/j.tetlet.2012.07.009

Reference yield:

4-nitro-aniline (100-01-6,104810-17-5) → 3-(bis(4-nitrophenyl)amino)phenol (1396649-85-6)

Guidance literature:

Multi-step reaction with 2 steps

1: neat (no solvent) / 110 °C / 5171.62 Torr / Sealed tube; Microwave irradiation

2: potassium carbonate / acetonitrile / 4 h / 100 °C / Green chemistry

With potassium carbonate; In acetonitrile;

DOI:10.1002/adsc.201700004

upstream raw materials:

3-(bis(4-nitrophenyl)amino)-2-iodocyclohex-2-enone

3-((4-nitrophenyl)amino)cyclohex-2-en-1-one

4-nitro-aniline

(4-nitrophenyl)-λ3-iodanediyl diacetate