(+/-)-2-[(1-benzyl-4-piperidinyl)methyl]-5-hydroxy-6-methoxy-1-indanone hydrochloride

Base Information

• Chemical Name: (+/-)-2-[(1-benzyl-4-piperidinyl)methyl]-5-hydroxy-6-methoxy-1-indanone hydrochloride
• CAS No.: 1260859-18-4
• Molecular Formula: C₂₃H₂₇NO₃*ClH
• Molecular Weight: 401.933

Synonyms:(+/-)-2-[(1-benzyl-4-piperidinyl)methyl]-5-hydroxy-6-methoxy-1-indanone hydrochloride

Chemical Property of (+/-)-2-[(1-benzyl-4-piperidinyl)methyl]-5-hydroxy-6-methoxy-1-indanone hydrochloride

Chemical Property:

Purity/Quality:

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Technology Process of (+/-)-2-[(1-benzyl-4-piperidinyl)methyl]-5-hydroxy-6-methoxy-1-indanone hydrochloride

There total 1 articles about (+/-)-2-[(1-benzyl-4-piperidinyl)methyl]-5-hydroxy-6-methoxy-1-indanone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.4%

donepezil (120014-06-4,142057-79-2,142057-80-5,142698-19-9) → (+/-)-2-[(1-benzyl-4-piperidinyl)methyl]-5-hydroxy-6-methoxy-1-indanone hydrochloride (1260859-18-4)

Guidance literature:

donepezil; With hydrogen bromide; acetic acid; In water; for 20h; water bath;

With potassium carbonate; In water; at 0 ℃;

With hydrogenchloride; In diethyl ether; isopropyl alcohol; Product distribution / selectivity;

upstream raw materials:

donepezil

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