(Z,Z)-(3S,4S)-2-benzyloxy-6-hydroxybenzoic acid 3-(1-benzyloxy-4-methoxymethoxy-deca-5,7-dien-9-yn)yl ester

Base Information

Chemical Name:(Z,Z)-(3S,4S)-2-benzyloxy-6-hydroxybenzoic acid 3-(1-benzyloxy-4-methoxymethoxy-deca-5,7-dien-9-yn)yl ester
CAS No.:760210-72-8
Molecular Formula:C₃₃H₃₄O₇
Molecular Weight:542.629
Hs Code.:

Synonyms:(Z,Z)-(3S,4S)-2-benzyloxy-6-hydroxybenzoic acid 3-(1-benzyloxy-4-methoxymethoxy-deca-5,7-dien-9-yn)yl ester

Suppliers and Price of (Z,Z)-(3S,4S)-2-benzyloxy-6-hydroxybenzoic acid 3-(1-benzyloxy-4-methoxymethoxy-deca-5,7-dien-9-yn)yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z,Z)-(3S,4S)-2-benzyloxy-6-hydroxybenzoic acid 3-(1-benzyloxy-4-methoxymethoxy-deca-5,7-dien-9-yn)yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z,Z)-(3S,4S)-2-benzyloxy-6-hydroxybenzoic acid 3-(1-benzyloxy-4-methoxymethoxy-deca-5,7-dien-9-yn)yl ester

There total 10 articles about (Z,Z)-(3S,4S)-2-benzyloxy-6-hydroxybenzoic acid 3-(1-benzyloxy-4-methoxymethoxy-deca-5,7-dien-9-yn)yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 154714-19-9
5-hydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one

: 760210-72-8
(Z,Z)-(3S,4S)-2-benzyloxy-6-hydroxybenzoic acid 3-(1-benzyloxy-4-methoxymethoxy-deca-5,7-dien-9-yn)yl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / dimethylformamide / 0.5 h / 0 °C

1.2: 96 percent / dimethylformamide / 20 °C

2.1: NaHMDS / tetrahydrofuran / 1 h / 0 °C

2.2: 77 percent / tetrahydrofuran / 4 h / 20 °C

3.1: 229 mg / TBAF / tetrahydrofuran / 1 h / 0 °C

With tetrabutyl ammonium fluoride; sodium hexamethyldisilazane; sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/ja047190o

Reference yield:

: 760210-91-1
2-Benzyloxy-6-hydroxy-benzoic acid (3Z,5Z)-(1S,2S)-1-(2-benzyloxy-ethyl)-2-methoxymethoxy-8-triisopropylsilanyl-octa-3,5-dien-7-ynyl ester

: 760210-72-8
(Z,Z)-(3S,4S)-2-benzyloxy-6-hydroxybenzoic acid 3-(1-benzyloxy-4-methoxymethoxy-deca-5,7-dien-9-yn)yl ester

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; for 1h;
DOI:10.1021/ja047190o

Reference yield:

: 149776-81-8
(Z)-hex-3-en-1,5-diynyl-triisopropylsilane

: 760210-72-8
(Z,Z)-(3S,4S)-2-benzyloxy-6-hydroxybenzoic acid 3-(1-benzyloxy-4-methoxymethoxy-deca-5,7-dien-9-yn)yl ester

Guidance literature:: Multi-step reaction with 6 steps

1.1: 77 percent / Zn(OTf)2; (+)-N-methylephedrine; Et₃N / toluene / 2 h / 20 °C

2.1: 86 percent / i-Pr₂NEt; DMAP / CH₂Cl₂ / 36 h / 20 °C / Heating

3.1: 98 percent / H₂; quinoline / Lindlar's catalyst / ethyl acetate / 21 h / 20 °C

4.1: 69 percent / DIBALH / CH₂Cl₂ / 1.5 h / 0 °C

5.1: NaHMDS / tetrahydrofuran / 1 h / 0 °C

5.2: 77 percent / tetrahydrofuran / 4 h / 20 °C

6.1: 229 mg / TBAF / tetrahydrofuran / 1 h / 0 °C

With quinoline; dmap; tetrabutyl ammonium fluoride; hydrogen; sodium hexamethyldisilazane; zinc trifluoromethanesulfonate; diisobutylaluminium hydride; (+)-N-methylephedrine; triethylamine; N-ethyl-N,N-diisopropylamine; Lindlar's catalyst; In tetrahydrofuran; dichloromethane; ethyl acetate; toluene;
DOI:10.1021/ja047190o