Technology Process of N--(R)-serine methylester
There total 6 articles about N--(R)-serine methylester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
4-methyl-morpholine; chloroformic acid ethyl ester;
In
ethyl acetate;
-15 deg C, 1 h, then RT, 12 h;
DOI:10.1055/s-1994-25484
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium carbonate / water / 16 h / 28 °C
2: triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 3 h / 20 °C
With
sodium carbonate; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
water; N,N-dimethyl-formamide;