5’O-Tritylinosine

Base Information

Chemical Name:5’O-Tritylinosine
CAS No.:4152-77-6
Molecular Formula:C₂₉H₂₆N₄O₅
Molecular Weight:510.549
Hs Code.:
Mol file:4152-77-6.mol

Synonyms:5’-O-trityl-inosine

Suppliers and Price of 5’O-Tritylinosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5’-O-Tritylinosine
100mg
$ 155.00

Cayman Chemical
KIN-59 ≥98%
100mg
$ 184.00

Cayman Chemical
KIN-59 ≥98%
50mg
$ 106.00

Cayman Chemical
KIN-59 ≥98%
10mg
$ 29.00

Biosynth Carbosynth
5-O-Tritylinosine
1 g
$ 2000.00

Biosynth Carbosynth
5-O-Tritylinosine
500 mg
$ 1250.00

Biosynth Carbosynth
5-O-Tritylinosine
250 mg
$ 750.00

Biosynth Carbosynth
5-O-Tritylinosine
100 mg
$ 400.00

Biosynth Carbosynth
5-O-Tritylinosine
50 mg
$ 250.00

ApexBio Technology
KIN-59
50mg
$ 130.00

Total 6 raw suppliers

Chemical Property of 5’O-Tritylinosine

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

5’-O-Tritylinosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description KIN59 is a purine riboside derivative that allosterically inhibits thymidine phosphorylase (TPase; IC50s = 44 and 67 μM for purified E. coli and human enzymes, respectively). Through this action, KIN59 blocks the conversion of thymidine to thymine. KIN59 inhibits TPase-induced angiogenesis in a chicken chorioallantoic membrane assay and reduces endothelial cell migration without impacting proliferation. KIN59 also inhibits the binding of fibroblast growth factor 2 (FGF2) to FGF receptor 1, preventing the growth and neovascularization of subcutaneous tumors induced by FGF2-transformed endothelial cells injected in immunodeficient nude mice.
Uses 5’O-Tritylinosine acts as an allosteric inhibitor of angiogenic enzyme thymidine phosphorylase. 5’-O-Tritylinosine acts as an allosteric inhibitor of angiogenic enzyme thymidine phosphorylase.

Technology Process of 5’O-Tritylinosine

There total 3 articles about 5’O-Tritylinosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%