2,2-dichlorovinyl-4'-nitroacetophenone oxime

Base Information

• Chemical Name: 2,2-dichlorovinyl-4'-nitroacetophenone oxime
• CAS No.: 1320360-70-0
• Molecular Formula: C₁₀H₈Cl₂N₂O₃
• Molecular Weight: 275.091
• Mol file: 1320360-70-0.mol

Synonyms:2,2-dichlorovinyl-4'-nitroacetophenone oxime

Chemical Property of 2,2-dichlorovinyl-4'-nitroacetophenone oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-dichlorovinyl-4'-nitroacetophenone oxime

There total 2 articles about 2,2-dichlorovinyl-4'-nitroacetophenone oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

4,4-dichloro-1-(4-nitrophenyl)but-3-en-1-one (807331-43-7) → 2,2-dichlorovinyl-4'-nitroacetophenone oxime (1320360-70-0)

Guidance literature:

With hydroxylamine; acetic acid; In ethanol; water; at 20 ℃; for 9h;

DOI:10.1016/j.tet.2011.05.110

Reference yield:

(E)-4,4,4-Trichloro-1-(4-nitro-phenyl)-but-2-en-1-one (78159-88-3) → 2,2-dichlorovinyl-4'-nitroacetophenone oxime (1320360-70-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Electrochemical reaction; Protic medium

2: hydroxylamine; acetic acid / ethanol; water / 9 h / 20 °C

With hydroxylamine; acetic acid; In ethanol; water;

DOI:10.1016/j.tet.2011.05.110

Reference yield: 86.0%

2,2-dichlorovinyl-4'-nitroacetophenone oxime (1320360-70-0) → 5-dichloromethyl-3-(4'-nitrophenyl)-2-isoxazoline (1320360-78-8)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 20 ℃;

DOI:10.1016/j.tet.2011.05.110

upstream raw materials:

(E)-4,4,4-Trichloro-1-(4-nitro-phenyl)-but-2-en-1-one

4,4-dichloro-1-(4-nitrophenyl)but-3-en-1-one

Downstream raw materials:

5-dichloromethyl-3-(4'-nitrophenyl)-2-isoxazoline