(R)-(phenylalanyl)-(S)-2-methylphenylalanine tert-butyl ester hydrochloride

Base Information

Chemical Name:(R)-(phenylalanyl)-(S)-2-methylphenylalanine tert-butyl ester hydrochloride
CAS No.:110510-52-6
Molecular Formula:C₂₃H₃₀N₂O₃*ClH
Molecular Weight:418.964
Hs Code.:

Synonyms:(R)-(phenylalanyl)-(S)-2-methylphenylalanine tert-butyl ester hydrochloride

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Chemical Property of (R)-(phenylalanyl)-(S)-2-methylphenylalanine tert-butyl ester hydrochloride

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Technology Process of (R)-(phenylalanyl)-(S)-2-methylphenylalanine tert-butyl ester hydrochloride

There total 2 articles about (R)-(phenylalanyl)-(S)-2-methylphenylalanine tert-butyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110510-51-5
(S)-2-((3R,4S)-3-Benzyloxycarbonylamino-2-oxo-4-phenyl-azetidin-1-yl)-2-methyl-3-phenyl-propionic acid tert-butyl ester

: 110510-52-6
(R)-(phenylalanyl)-(S)-2-methylphenylalanine tert-butyl ester hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; at 50 ℃; for 12h;
DOI:10.1021/ja00255a063

Reference yield:

: 110510-50-4
(S)-2-((3R,4S)-3-Benzyloxycarbonylamino-2-oxo-4-phenyl-azetidin-1-yl)-propionic acid tert-butyl ester

: 110510-52-6
(R)-(phenylalanyl)-(S)-2-methylphenylalanine tert-butyl ester hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

2: H₂, 1 N HCl / 10 percent Pd-C / methanol / 12 h / 50 °C

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1021/ja00255a063