methyl 3,6-di-O-<2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-3,4,6-tri-O-benzyl-α-D-mannopyranosyl>-2,4-di-O-benzyl-α-D-mannopyranoside

Base Information

• Chemical Name: methyl 3,6-di-O-<2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-3,4,6-tri-O-benzyl-α-D-mannopyranosyl>-2,4-di-O-benzyl-α-D-mannopyranoside
• CAS No.: 68601-78-5
• Molecular Formula: C₁₁₅H₁₂₀N₂O₃₄
• Molecular Weight: 2074.21
• Mol file: 68601-78-5.mol

Synonyms:methyl 3,6-di-O-<2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-3,4,6-tri-O-benzyl-α-D-mannopyranosyl>-2,4-di-O-benzyl-α-D-mannopyranoside

Chemical Property of methyl 3,6-di-O-<2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-3,4,6-tri-O-benzyl-α-D-mannopyranosyl>-2,4-di-O-benzyl-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3,6-di-O-<2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-3,4,6-tri-O-benzyl-α-D-mannopyranosyl>-2,4-di-O-benzyl-α-D-mannopyranoside

There total 2 articles about methyl 3,6-di-O-<2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-3,4,6-tri-O-benzyl-α-D-mannopyranosyl>-2,4-di-O-benzyl-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl fluoride (130539-42-3,147157-97-9,177966-56-2) + methyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl-(1->3))-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl-(1->6))-2,4-di-O-benzyl-α-D-mannopyranoside (68601-73-0) → methyl 3,6-di-O-<2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-3,4,6-tri-O-benzyl-α-D-mannopyranosyl>-2,4-di-O-benzyl-α-D-mannopyranoside (68601-78-5)

Guidance literature:

3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl fluoride; methyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl-(1->3))-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl-(1->6))-2,4-di-O-benzyl-α-D-mannopyranoside; In toluene; for 0.166667h; Molecular sieve; Inert atmosphere;

With bis(cyclopentadienyl)hafnium dichloride; silver trifluoromethanesulfonate; In toluene; at 0 - 40 ℃; for 8h; Inert atmosphere;

DOI:10.1016/j.bmcl.2014.07.074

Reference yield:

→ C115H120N2O34 (68601-78-5)

Guidance literature:

Chlorid (18), Diol (13);

DOI:10.1016/S0008-6215(00)83724-6

Reference yield:

methyl 3,6-di-O-<2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-3,4,6-tri-O-benzyl-α-D-mannopyranosyl>-2,4-di-O-benzyl-α-D-mannopyranoside (68601-78-5) → C99H116N2O30

Guidance literature:

With ethylenediamine; In butan-1-ol; at 100 ℃;

DOI:10.1016/j.bmcl.2014.07.074

upstream raw materials:

3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl fluoride

methyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl-(1->3))-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl-(1->6))-2,4-di-O-benzyl-α-D-mannopyranoside

Downstream raw materials:

methyl 3,6-di-O-<2-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-3,4,6-tri-O-benzyl-α-D-mannopyranosyl>-2,4-di-O-benzyl-α-D-mannopyranoside