8-FLUORO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE HYDROCHLORIDE

Base Information

Chemical Name:8-FLUORO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE HYDROCHLORIDE
CAS No.:847173-36-8
Molecular Formula:C₁₀H₁₂FN
Molecular Weight:165.21
Hs Code.:
Mol file:847173-36-8.mol

Synonyms:8-FLUORO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE HYDROCHLORIDE

Suppliers and Price of 8-FLUORO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE HYDROCHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
8-FLUORO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE HYDROCHLORIDE 95.00%
5MG
$ 503.58

Total 2 raw suppliers

Chemical Property of 8-FLUORO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE HYDROCHLORIDE

Chemical Property:

PSA：12.03000
LogP:2.71190

Purity/Quality:: 8-FLUORO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 8-FLUORO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE HYDROCHLORIDE

There total 2 articles about 8-FLUORO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 13790-88-0
7-fluoro-1-tetralone oxime

: 847173-36-8
8-fluoro-2,3,4,5-tetrahydro-1H-benzo[b]azepine

Guidance literature:: 7-fluoro-3,4-dihydronaphthalen-1(2H)-one oxime; With diisobutylaluminium hydride; In hexane; dichloromethane; at 0 - 20 ℃; for 2h;

With sodium fluoride; In hexane; dichloromethane; water; at 0 - 20 ℃; for 2h;
DOI:10.1016/j.ejmech.2021.113383

Reference yield:

: 2840-44-0
7-fluoro-3,4-dihydronaphthalen-1(2H)-one

: 847173-36-8
8-fluoro-2,3,4,5-tetrahydro-1H-benzo[b]azepine

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydroxylamine hydrochloride; pyridine / 3 h / 20 °C

2.1: diisobutylaluminium hydride / hexane; dichloromethane / 2 h / 0 - 20 °C

2.2: 2 h / 0 - 20 °C

With pyridine; hydroxylamine hydrochloride; diisobutylaluminium hydride; In hexane; dichloromethane;
DOI:10.1016/j.ejmech.2021.113383