4-(azidomethyl)phenyldiisopropylsilane

Base Information

• Chemical Name: 4-(azidomethyl)phenyldiisopropylsilane
• CAS No.: 1133959-33-7
• Molecular Formula: C₁₃H₂₁N₃Si
• Molecular Weight: 247.415
• Mol file: 1133959-33-7.mol

Synonyms:4-(azidomethyl)phenyldiisopropylsilane

Chemical Property of 4-(azidomethyl)phenyldiisopropylsilane

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-(azidomethyl)phenyldiisopropylsilane

There total 2 articles about 4-(azidomethyl)phenyldiisopropylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4-(diisopropylsilanyl)-phenyl methanol (475160-70-4) → 4-(azidomethyl)phenyldiisopropylsilane (1133959-33-7)

Guidance literature:

With sodium azide; carbon tetrabromide; triphenylphosphine; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

DOI:10.1021/jo9000965

Reference yield:

C14H24O3SSi → 4-(azidomethyl)phenyldiisopropylsilane (1133959-33-7)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; for 6h;

DOI:10.1016/j.ejmech.2018.02.017

Reference yield: 87.0%

4-(azidomethyl)phenyldiisopropylsilane (1133959-33-7) + 4-N-(hexynoyl)gemcitabine → 4-N-[4-(1-(4-(diisopropylsilyl)benzyl)-1H-1,2,3-triazol-4-yl)butanoyl]-2'-deoxy-2',2'-difluorocytidine

Guidance literature:

With copper(I) sulfate; sodium L-ascorbate; In water; tert-butyl alcohol; at 20 ℃; for 6h;

DOI:10.1016/j.ejmech.2018.02.017

upstream raw materials:

4-(diisopropylsilanyl)-phenyl methanol