2-(4-Fluorophenyl)benzo[b]thiophene

Base Information

Chemical Name:2-(4-Fluorophenyl)benzo[b]thiophene
CAS No.:936734-96-2
Molecular Formula:C₁₄H₉FS
Molecular Weight:228.29
Hs Code.:
DSSTox Substance ID:DTXSID701292306
Nikkaji Number:J2.760.674A

Synonyms:936734-96-2;2-(4-Fluorophenyl)benzo[b]thiophene;DTXSID701292306;2-(4-Fluoro-phenyl)-benzo[b]thiophene

Suppliers and Price of 2-(4-Fluorophenyl)benzo[b]thiophene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-Fluorophenyl)benzo[b]thiophene

Chemical Property:

XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:228.04089962
Heavy Atom Count:16
Complexity:235

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(S2)C3=CC=C(C=C3)F

Technology Process of 2-(4-Fluorophenyl)benzo[b]thiophene

There total 28 articles about 2-(4-Fluorophenyl)benzo[b]thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1415694-10-8
1-((4-fluorophenyl)ethynyl)-2-iodobenzene

: 936734-96-2
2-(4-fluoro-phenyl)-benzo[b]thiophene

Guidance literature:: With copper diacetate; potassium ethyl xanthogenate; (R)-1,1'-binaphthyl-2,2'-diamine; In N,N-dimethyl-formamide; at 80 ℃; for 35h; Inert atmosphere;
DOI:10.1039/c3ob26915a

Reference yield: 95.0%

: 460-00-4
1-Bromo-4-fluorobenzene

: 95-15-8,11095-43-5
Benzo[b]thiophene

: 936734-96-2
2-(4-fluoro-phenyl)-benzo[b]thiophene

Guidance literature:: Benzo[b]thiophene; With ethylmagnesium chloride; N-cyclohexyl-cyclohexanamine; In tetrahydrofuran; at 60 ℃; for 24h;

1-Bromo-4-fluorobenzene; With dichloro-[1,3-bis(2,6-diisopropylpenyl)-2-imidazolidinyliden]-(3-chloropyridyl)palladium(II); In tetrahydrofuran; at 20 ℃; for 22h;
DOI:10.1016/j.tetlet.2011.12.108

Reference yield: 92.0%

: 98437-23-1
benzo[b]thiophene-2-boronic acid

: 460-00-4
1-Bromo-4-fluorobenzene

: 936734-96-2
2-(4-fluoro-phenyl)-benzo[b]thiophene

Guidance literature:: 1-Bromo-4-fluorobenzene; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 20 ℃; for 0.333333h; Inert atmosphere;

benzo[b]thiophene-2-boronic acid; With sodium hydrogencarbonate; In 1,4-dioxane; water; for 1h; Reflux; Inert atmosphere;
DOI:10.1002/anie.201701409