2-(3,4-Dibromophenyl)acetonitrile

Base Information

Chemical Name:2-(3,4-Dibromophenyl)acetonitrile
CAS No.:249647-27-6
Molecular Formula:C₈H₅Br₂N
Molecular Weight:274.942
Hs Code.:
DSSTox Substance ID:DTXSID601306681

Synonyms:2-(3,4-dibromophenyl)acetonitrile;249647-27-6;3,4-Dibromobenzeneacetonitrile;SCHEMBL7198498;DTXSID601306681

Suppliers and Price of 2-(3,4-Dibromophenyl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2-(3,4-Dibromophenyl)acetonitrile

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:274.87682
Heavy Atom Count:11
Complexity:172

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1CC#N)Br)Br

Technology Process of 2-(3,4-Dibromophenyl)acetonitrile

There total 6 articles about 2-(3,4-Dibromophenyl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 64382-93-0
1,2-dibromo-4-(bromomethyl)benzene

: 151-50-8
potassium cyanide

: 249647-27-6
3,4-dibromophenylacetonitrile

Guidance literature:: In ethanol; water; for 10h; Heating;
DOI:10.1016/S0968-0896(03)00220-7

Reference yield:

: 619-42-1
4-methoxycarbonylphenyl bromide

: 249647-27-6
3,4-dibromophenylacetonitrile

Guidance literature:: Multi-step reaction with 5 steps

1: NBS; H₂SO₄ / 15 h / 20 °C

2: LiAlH₄ / diethyl ether / 0.5 h / 20 °C

3: Et₃N / CH₂Cl₂ / 1 h / 0 - 20 °C

4: NaI / butan-2-one / 3 h / Heating

5: dimethylformamide / 15 h / 50 °C

With N-Bromosuccinimide; lithium aluminium tetrahydride; sulfuric acid; triethylamine; sodium iodide; In diethyl ether; dichloromethane; N,N-dimethyl-formamide; butanone; 1: Bromination / 2: Reduction / 3: Sulfonylation / 4: Iodination / 5: Substitution;
DOI:10.1021/jm990229t

Reference yield:

: 51329-16-9
3,4-dibromobenzoic acid methyl ester

: 249647-27-6
3,4-dibromophenylacetonitrile

Guidance literature:: Multi-step reaction with 4 steps

1: LiAlH₄ / diethyl ether / 0.5 h / 20 °C

2: Et₃N / CH₂Cl₂ / 1 h / 0 - 20 °C

3: NaI / butan-2-one / 3 h / Heating

4: dimethylformamide / 15 h / 50 °C

With lithium aluminium tetrahydride; triethylamine; sodium iodide; In diethyl ether; dichloromethane; N,N-dimethyl-formamide; butanone; 1: Reduction / 2: Sulfonylation / 3: Iodination / 4: Substitution;
DOI:10.1021/jm990229t