5-(4-Bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole

Base Information

Chemical Name:5-(4-Bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole
CAS No.:845306-17-4
Molecular Formula:C9H6 Br F N2 O
Molecular Weight:257.062
Hs Code.:2934999090
DSSTox Substance ID:DTXSID20699450
Wikidata:Q82630376
Mol file:845306-17-4.mol

Synonyms:5-(4-BROMO-2-FLUOROPHENYL)-3-METHYL-1,2,4-OXADIAZOLE;845306-17-4;SCHEMBL4031243;DTXSID20699450;HSVLDONTNWZJBX-UHFFFAOYSA-N;MFCD09261267;AKOS026674766;MB07203;CS-0456121

Suppliers and Price of 5-(4-Bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
5-(4-Bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole
500 mg
$ 573.00

Crysdot
5-(4-Bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole 97%
1g
$ 567.00

Apolloscientific
5-(4-Bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole
500mg
$ 358.00

American Custom Chemicals Corporation
5-(4-BROMO-2-FLUOROPHENYL)-3-METHYL-1,2,4-OXADIAZOLE 95.00%
5MG
$ 495.73

Total 2 raw suppliers

Chemical Property of 5-(4-Bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole

Chemical Property:

PSA：38.92000
LogP:2.94660
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:255.96475
Heavy Atom Count:14
Complexity:207

Purity/Quality:

99%+ ^*data from raw suppliers

5-(4-Bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NOC(=N1)C2=C(C=C(C=C2)Br)F

Technology Process of 5-(4-Bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole

There total 2 articles about 5-(4-Bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 845306-18-5
C₁₁H₁₂BrFN₂O

: 845306-17-4
5-(4-bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole

Guidance literature:: With sodium hydroxide; hydroxylamine hydrochloride; acetic acid; In 1,4-dioxane; at 20 - 90 ℃; for 3.5h;

Reference yield:

: 18871-66-4
N,N-dimethylacetamide dimethyl acetal

: 292621-45-5
4-bromo-2-fluorobenzamide

: 845306-17-4
5-(4-bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole

Guidance literature:: N,N-dimethylacetamide dimethyl acetal; 4-bromo-2-fluorobenzamide; at 120 ℃; for 2h;

With sodium hydroxide; hydroxylamine hydrochloride; acetic acid; In 1,4-dioxane; water; at 20 - 90 ℃; for 3.5h;

With sodium hydrogencarbonate; In water; pH=9;

Reference yield:

: 884199-25-1
1-(1-methylethyl)-4-[(3S)-3-pyrrolidinylcarbonyl]piperazine

: 845306-17-4
5-(4-bromo-2-fluorophenyl)-3-methyl-1,2,4-oxadiazole

: 1-({(3S)-1-[3-fluoro-4-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl]-3-pyrrolidinyl}carbonyl)-4-(1-methylethyl)piperazine

Guidance literature:: With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; DavePhos; In 1,2-dimethoxyethane; at 20 - 75 ℃; for 4h;