O,O-Dimethyl-curvulin

Base Information

• Chemical Name: O,O-Dimethyl-curvulin
• CAS No.: 36440-20-7
• Molecular Formula: C₁₄H₁₈O₅
• Molecular Weight: 266.294
• Mol file: 36440-20-7.mol

Synonyms:O,O-Dimethyl-curvulin

Chemical Property of O,O-Dimethyl-curvulin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O,O-Dimethyl-curvulin

There total 2 articles about O,O-Dimethyl-curvulin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

3,5-dimethoxy-2-(trimethylsilyl)phenyl trifluoromethanesulfonate (1203549-54-5) + ethyl acetoacetate (141-97-9) → O,O-Dimethyl-curvulin (36440-20-7)

Guidance literature:

With potassium fluoride; 18-crown-6 ether; In tetrahydrofuran; at 20 ℃; regioselective reaction; Inert atmosphere;

DOI:10.1021/ol1000796

Reference yield:

→ O,O-Dimethyl-curvulin (36440-20-7)

Guidance literature:

Aus jedem der beiden Mono-O-methyl-curvulin-Isomeren (F: 84grad bzw. F: 206grad), Diazomethan, Ae.;

DOI:10.1016/0040-4020(63)80011-3

upstream raw materials:

3,5-dimethoxy-2-(trimethylsilyl)phenyl trifluoromethanesulfonate

ethyl acetoacetate

Refernces